Cellular senescence and premature aging in Down Syndrome

Down syndrome (DS) is a genetic disorder caused by an extra copy of chromosome 21, resulting in cognitive impairment, physical abnormalities, and an increased risk of age-related co-morbidities. Individuals with DS exhibit accelerated aging, which has been attributed to several cellular mechanisms,...

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Veröffentlicht in:	Mechanisms of ageing and development 2023-06, Vol.212, p.111824-111824, Article 111824
Hauptverfasser:	Peng, Lianli, Baradar, Alireza A., Aguado, Julio, Wolvetang, Ernst
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular senescence Down syndrome Premature aging
Online-Zugang:	Volltext
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