Diagnostic and prognostic biomarkers for tubulointerstitial fibrosis

Renal fibrosis is the final common pathophysiological pathway in chronic kidney disease (CKD) regardless of the underlying cause of kidney injury. Tubulointerstitial fibrosis (TIF) is considered to be the key pathological predictor of CKD progression. Currently, the gold‐standard tool to identify TI...

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Veröffentlicht in:	The Journal of physiology 2023-07, Vol.601 (14), p.2801-2826
Hauptverfasser:	Rende, Umut, Guller, Anna, Goldys, Ewa M., Pollock, Carol, Saad, Sonia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Biomarkers Biomarkers - metabolism Biopsy chronic kidney disease Fibrosis Glomerular filtration rate Kidney - metabolism Kidney diseases non‐invasive diagnostics Prognosis renal fibrosis Renal Insufficiency, Chronic - diagnosis Renal Insufficiency, Chronic - etiology Renal Insufficiency, Chronic - metabolism tubulointerstitial fibrosis
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