Shifts in mutation spectra enhance access to beneficial mutations

Biased mutation spectra are pervasive, with wide variation in the magnitude of mutational biases that influence genome evolution and adaptation. How do such diverse biases evolve? Our experiments show that changing the mutation spectrum allows populations to sample previously undersampled mutational...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2023-05, Vol.120 (22), p.e2207355120
Hauptverfasser:	Sane, Mrudula, Diwan, Gaurav D, Bhat, Bhoomika A, Wahl, Lindi M, Agashe, Deepa
Format:	Artikel
Sprache:	eng
Schlagworte:	Acclimatization Adaptation, Physiological - genetics Bias DNA repair Evolution Evolution, Molecular Genes Genome Genomes Mutation Phylogeny Pleiotropy Selection, Genetic Spectra
Online-Zugang:	Volltext
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