Comparison of Aptamer Signaling Mechanisms Reveals Disparities in Sensor Response and Strategies to Eliminate False Signals

Aptamers are nucleic acid-based affinity reagents that have been incorporated into a variety of molecular sensor formats. However, many aptamer sensors exhibit insufficient sensitivity and specificity for real-world applications, and although considerable effort has been dedicated to improving sensi...

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Veröffentlicht in:	Journal of the American Chemical Society 2023-06, Vol.145 (22), p.12407-12422
Hauptverfasser:	Alkhamis, Obtin, Canoura, Juan, Willis, Connor, Wang, Linlin, Perry, Jacob, Xiao, Yi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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