Combination of novel oncolytic herpesvirus with paclitaxel as an efficient strategy for breast cancer therapy

Background New strategies are needed to improve the treatment of patients with breast cancer (BC). Oncolytic virotherapy is a promising new tool for cancer treatment but still has a limited overall durable antitumor response. A novel replicable recombinant oncolytic herpes simplex virus type 1 calle...

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Veröffentlicht in:	Journal of medical virology 2023-05, Vol.95 (5), p.e28768-n/a
Hauptverfasser:	Deng, Xinyue, Shen, Yinan, Yi, Ming, Zhang, Chaomei, Zhao, Bin, Zhong, Guansheng, WeiyangLou, Xue, Dixuan, Leng, Qi, Ding, Jun, zhao, Ronghua, Jia, Weiguo, Dong, Chenfang, Dai, Zhijun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticancer properties Antitumor activity Breast cancer Cancer therapies CD4 antigen CD8 antigen CD8-Positive T-Lymphocytes Cell Line, Tumor Dendritic cells Flow cytometry Herpes simplex Herpes viruses Herpesvirus 1, Human Humans Immune response Immune system Immunohistochemistry Immunostimulation Immunotherapy Inflammation Lung cancer lung metastasis Lymphocytes Lymphocytes T Lymphoid cells Macrophages Metastases Metastasis Mice Myeloid cells Neoplasms - pathology Oncolysis Oncolytic Virotherapy Oncolytic Viruses - genetics Paclitaxel Paclitaxel - pharmacology Paclitaxel - therapeutic use PTX Pulmonary lesions Suppressor cells Tumor Microenvironment Tumors VG161 Virology Viruses Xenotransplantation
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