Development of low-cost, weight-adjustable clofazimine mini-tablets for treatment of tuberculosis in pediatrics

Clofazimine (CFZ) is an important component of the World Health Organization's (WHO) recommended all-oral drug regimen for treatment of multi-drug resistant tuberculosis (MDR-TB). However, the lack of a dividable oral dosage form has limited the use of the drug in pediatric populations, who may...

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Veröffentlicht in:	European journal of pharmaceutical sciences 2023-08, Vol.187, p.106470-106470, Article 106470
Hauptverfasser:	Warnken, Zachary, Trementozzi, Andrea, Martins, Patricia P., Parekh, Jagruti, Koleng, John J., Smyth, Hugh D.C., Brunaugh, Ashlee
Format:	Artikel
Sprache:	eng
Schlagworte:	Clofazimine Direct compression Mini-tablets Pediatrics Personalized therapy Poorly water soluble Tuberculosis
Online-Zugang:	Volltext
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