Challenging the Prevailing Therapeutic Dogma for Prostate Cancer: The Case for an Overlap Syndrome

Challenging the Prevailing Therapeutic Dogma for Prostate Cancer: The Case for an Overlap Syndrome

There is a need to understand what accounts for the modest impact of therapy on overall survival among men with potentially lethal prostate cancer. Given converging lines of evidence, we hypothesize that in a subset of men, prostate cancer is part of an “overlap syndrome” of age-related illnesses wi...

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Veröffentlicht in:European urology 2024-01, Vol.85 (1), p.3-7
Hauptverfasser: Logothetis, Christopher J., Hahn, Andrew W.
Format: Artikel
Sprache:eng
Schlagworte:
Humans
Male
Prostatic Neoplasms
Syndrome
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Beschreibung
Zusammenfassung:There is a need to understand what accounts for the modest impact of therapy on overall survival among men with potentially lethal prostate cancer. Given converging lines of evidence, we hypothesize that in a subset of men, prostate cancer is part of an “overlap syndrome” of age-related illnesses with shared biologic vulnerability.
ISSN:0302-2838
1873-7560
DOI:10.1016/j.eururo.2023.04.015