The effect of lipopolysaccharide on liver homeostasis and diseases based on the mutual interaction of macrophages, autophagy, and damage-associated molecular patterns in male F344/DuCrlCrlj rats

Lipopolysaccharide (LPS) has dose-dependent biphasic functions (cell protective versus cell toxic). To clarify the different effects of LPS on liver homeostasis or liver diseases, comparisons were made between low and high doses of LPS, in terms of the mutual relation of hepatic macrophages, autopha...

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Veröffentlicht in:	Veterinary pathology 2023-07, Vol.60 (4), p.461-472
Hauptverfasser:	Takami, Yuki, Tanaka, Miyuu, Izawa, Takeshi, Kuwamura, Mitsuru, Yamate, Jyoji
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy HMGB1 Protein - pharmacology Inflammation - pathology Inflammation - veterinary Lipopolysaccharides - toxicity Liver - pathology Liver Diseases - pathology Liver Diseases - veterinary Macrophages - pathology Male Rats Rats, Inbred F344
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