The mTOR Signaling Pathway Interacts with the ER Stress Response and the Unfolded Protein Response in Cancer

The mTOR complex 1 (mTORC1) coordinates several important environmental and intracellular cues to control a variety of biological processes, such as cell growth, survival, autophagy, and metabolism, in response to energy levels, growth signals, and nutrients. The endoplasmic reticulum (ER) is a cruc...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2023-08, Vol.83 (15), p.2450-2460
Hauptverfasser:	Mafi, Sahar, Ahmadi, Elham, Meehan, Eileen, Chiari, Conner, Mansoori, Behzad, Sadeghi, Hossein, Milani, Sahar, Jafarinia, Morteza, Taeb, Shahram, Mafakheri Bashmagh, Bayan, Mansoorian, Seyed Mohammad Ali, Soltani-Zangbar, Mohammad Sadegh, Wang, Kepeng, Rostamzadeh, Davoud
Format:	Artikel
Sprache:	eng
Schlagworte:	Endoplasmic Reticulum Stress Humans Neoplasms Phosphatidylinositol 3-Kinases - metabolism Signal Transduction - physiology TOR Serine-Threonine Kinases - metabolism Unfolded Protein Response
Online-Zugang:	Volltext
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