Clinical characteristics of heart failure with reduced ejection fraction patients with rare pathogenic variants in dilated cardiomyopathy‐associated genes: A subgroup analysis of the PARADIGM‐HF trial

Aims To evaluate the prevalence of pathogenic variants in genes associated with dilated cardiomyopathy (DCM) in a clinical trial population with heart failure and reduced ejection fraction (HFrEF) and describe the baseline characteristics by variant carrier status. Methods and results This was a pos...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	European journal of heart failure 2023-08, Vol.25 (8), p.1256-1266
Hauptverfasser:	Barat, Ana, Chen, Chien‐Wei, Patel‐Murray, Natasha, McMurray, John J.V., Packer, Milton, Solomon, Scott D., Desai, Akshay S., Rouleau, Jean L., Zile, Michael R., Attari, Zenab, Zhang, Cong, Xu, Huilei, Hartman, Nicole, Hon, Claudia, Healey, Margaret, Chutkow, William, O'Donnell, Christopher J., Jacob, Jaison, Lefkowitz, Marty, Mendelson, Michael M., Wandel, Simon, Yates, Denise, Gimpelewicz, Claudio
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical characteristics Dilated cardiomyopathy HFrEF Prevalence Rare truncating pLoF variants Titin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!