Quinolyl‐Based PGM Metallarectangles: Antiproliferative Activity, DNA and BSA Protein Interactions, and a Molecular Docking Perspective

The increased success of small metal‐containing molecules as pharmaceutical agents has prompted investigations into the pharmacological activity of a different class of metal‐based compounds; supramolecular coordination complexes (SCCs). Such complexes have been extensively investigated for their an...

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Veröffentlicht in:	Chembiochem : a European journal of chemical biology 2023-07, Vol.24 (13), p.e202300271-n/a
Hauptverfasser:	Golding, Taryn M., Omondi, Reinner O., Biswas, Supratim, Chakraborty, Suparna, Prince, Sharon, Smith, Gregory S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer Anticancer properties Antineoplastic Agents - chemistry Antiproliferatives Antitumor activity Bovine serum albumin Breast cancer Breast Neoplasms Calf thymus Cell Line, Tumor Cisplatin Coordination Complexes - chemistry Coordination compounds Cymene Cytotoxicity Deoxyribonucleic acid DNA DNA - chemistry Drug development Epithelial cells Epithelium Female Humans Ligands MCF-7 Cells Metallarectangles Molecular docking Molecular Docking Simulation Molecular Simulations PGM Protein interaction Quinoline Quinolines Ruthenium - chemistry Ruthenium - pharmacology Serum albumin Serum Albumin, Bovine - chemistry Tumor cell lines
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