Single-Molecule Monitoring of Membrane Association of the Necroptosis Executioner MLKL with Discernible Anchoring and Insertion Dynamics

The dynamics of membrane proteins that are well-folded in water and become functional after self-insertion into cell membranes is not well understood. Herein we report on single-molecule monitoring of membrane association dynamics of the necroptosis executioner MLKL. We observed that, upon landing,...

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Veröffentlicht in:Nano letters 2023-06, Vol.23 (11), p.4770-4777
Hauptverfasser: Yang, Chenguang, He, Xiaolong, Wang, Hao, Lin, Zhao, Hou, Wenqing, Lu, Ying, Hu, Shuxin, Li, Ming
Format: Artikel
Sprache:eng
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