Investigation of anti-PF4 versus anti-PF4/heparin reactivity using fluid-phase enzyme immunoassay for 4 anti-PF4 disorders: classic heparin-induced thrombocytopenia (HIT), autoimmune HIT, vaccine-induced immune thrombotic thrombocytopenia, and spontaneous HIT

Four platelet-activating anti-platelet factor 4 (PF4) disorders have been recognized: classic heparin-induced thrombocytopenia (cHIT), autoimmune heparin-induced thrombocytopenia (aHIT), spontaneous heparin-induced thrombocytopenia (SpHIT), and vaccine-induced immune thrombotic thrombocytopenia (VIT...

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Veröffentlicht in:	Journal of thrombosis and haemostasis 2023-08, Vol.21 (8), p.2268-2276
Hauptverfasser:	Warkentin, Theodore E., Arnold, Donald M., Sheppard, Jo-Ann I., Moore, Jane C., Kelton, John G., Nazy, Ishac
Format:	Artikel
Sprache:	eng
Schlagworte:	antibodies heparin Heparin - adverse effects Humans Immunoenzyme Techniques Immunoglobulin G platelet factor 4 Purpura, Thrombocytopenic, Idiopathic Sinus Thrombosis, Intracranial thrombocytopenia Thrombocytopenia - chemically induced Thrombocytopenia - diagnosis Thrombosis Vaccines
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