Proof of concept for detection of staphylococcal enterotoxins in platelet concentrates as a novel safety mitigation strategy

Background and Objectives Staphylococcus aureus is a predominant contaminant of platelet concentrates (PCs) that can evade detection during screening with culture methods. Importantly, S. aureus produces staphylococcal enterotoxins (SEs) during PC storage, which are linked to slow growth and enhance...

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Veröffentlicht in:	Vox sanguinis 2023-07, Vol.118 (7), p.543-550
Hauptverfasser:	Chi, Sylvia Ighem, Yousuf, Basit, Paredes, Carina, Bearne, Jennifer, McDonald, Carl, Ramirez‐Arcos, Sandra
Format:	Artikel
Sprache:	eng
Schlagworte:	Biofilms Contaminants enterotoxins Enzyme-linked immunosorbent assay Exotoxins Gene expression Genes Genomic analysis platelet concentrates Platelets Safety staphylococcal exotoxins Staphylococcus aureus Storage Toxins Transcriptomes Transcriptomics Transfusion Western blotting
Online-Zugang:	Volltext
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