Association of OPRK1 rs963549 and rs997917 polymorphisms with opioid use disorder and related phenotypes

To evaluate the association between rs963549 and rs997917 and opioid use disorder (OUD) and related phenotypes. A sample of 208 individuals with (n = 100) and without (n = 108) OUD were enrolled. rs963549 and rs997917 were analyzed by PCR-RFLP. Craving, opioid withdrawal and the intensity of depress...

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Veröffentlicht in:	Pharmacogenomics 2023-04, Vol.24 (6), p.325-334
Hauptverfasser:	Özkan-Kotiloğlu, Selin, Kaya-Akyüzlü, Dilek, Yalçın-Şahiner, Şafak, Ayaz, Nagihan
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics, Opioid Humans Opioid-Related Disorders - drug therapy Opioid-Related Disorders - genetics Phenotype Polymorphism, Single Nucleotide - genetics Receptors, Opioid, kappa - genetics Substance Withdrawal Syndrome - drug therapy Substance Withdrawal Syndrome - genetics
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