Twenty-Five Years of Lung Transplantation in Medellín: Overcoming the Challenges of an Emerging Country
The first successful lung transplant in Colombia was performed on October 28, 1997 in Medellín by Alberto Villegas Hernández at the “Clínica Cardiovascular Santa María” today called the Cardio VID Clinic. Here we present both survival outcomes and characteristics of the oldest and most experienced l...
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Veröffentlicht in: | Seminars in thoracic and cardiovascular surgery 2024, Vol.36 (3), p.369-375 |
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creator | Vinck, Eric E. Zapata, Ricardo A. Rendón, Juan C. Medina, Camilo Montoya Escobar, José J. Tobón, Marcela P. Colorado, Maria F. Vargas, Alberto R. Uribe, Juan D. Villegas, Alejandro Londoño |
description | The first successful lung transplant in Colombia was performed on October 28, 1997 in Medellín by Alberto Villegas Hernández at the “Clínica Cardiovascular Santa María” today called the Cardio VID Clinic. Here we present both survival outcomes and characteristics of the oldest and most experienced lung transplant program in Colombia. We conducted a retrospective study of all patients taken to lung transplantation at the Cardio VID Clinic in Medellín, Colombia from October 1997 to October 2022. Patient information from our institutional database and transplant archives were retrieved and reviewed. From October 1997 to October 2022, a total of 153 patients underwent orthotopic lung transplantation at our institution in Medellín, Colombia. Mean recipient age was 48 ± 13 years, the youngest patient was 15 years old and the oldest patient was 73 years old at the time of transplant. Seventy-four (48.4%) patients were men and seventy-nine (51.6%) were women. Uncensored lung transplant survival in Medellin at 1 month, 1 year, 5 years, and 10 years were 68%, 50%, 31%, and 12%, respectively. Although health care coverage in Colombia reaches nearly 100%, socioeconomic hurdles during post-transplant care, nonreturning patients, infections, and traumatic donor deaths lead to high mortality rates. Due to these factors, establishing successful and sustainable lung transplant programs in these settings is challenging. |
doi_str_mv | 10.1053/j.semtcvs.2023.03.001 |
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Here we present both survival outcomes and characteristics of the oldest and most experienced lung transplant program in Colombia. We conducted a retrospective study of all patients taken to lung transplantation at the Cardio VID Clinic in Medellín, Colombia from October 1997 to October 2022. Patient information from our institutional database and transplant archives were retrieved and reviewed. From October 1997 to October 2022, a total of 153 patients underwent orthotopic lung transplantation at our institution in Medellín, Colombia. Mean recipient age was 48 ± 13 years, the youngest patient was 15 years old and the oldest patient was 73 years old at the time of transplant. Seventy-four (48.4%) patients were men and seventy-nine (51.6%) were women. Uncensored lung transplant survival in Medellin at 1 month, 1 year, 5 years, and 10 years were 68%, 50%, 31%, and 12%, respectively. Although health care coverage in Colombia reaches nearly 100%, socioeconomic hurdles during post-transplant care, nonreturning patients, infections, and traumatic donor deaths lead to high mortality rates. Due to these factors, establishing successful and sustainable lung transplant programs in these settings is challenging.</description><identifier>ISSN: 1043-0679</identifier><identifier>ISSN: 1532-9488</identifier><identifier>EISSN: 1532-9488</identifier><identifier>DOI: 10.1053/j.semtcvs.2023.03.001</identifier><identifier>PMID: 37164144</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Aged ; Colombia ; Developing Countries ; Female ; History, 21st Century ; Humans ; Lung Diseases - diagnosis ; Lung Diseases - mortality ; Lung Diseases - surgery ; Lung transplantation ; Lung Transplantation - adverse effects ; Lung Transplantation - mortality ; Male ; Medellín ; Middle Aged ; Retrospective Studies ; Risk Factors ; Survival ; Time Factors ; Treatment Outcome ; Young Adult</subject><ispartof>Seminars in thoracic and cardiovascular surgery, 2024, Vol.36 (3), p.369-375</ispartof><rights>2023 Elsevier Inc.</rights><rights>Copyright © 2023 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c313t-4139ba0e18552f0d42a7ed6eebeaba75150a6f26a2444783c8c0616ab1a41c193</cites><orcidid>0000-0002-9728-3910</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S1043067923000370$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37164144$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vinck, Eric E.</creatorcontrib><creatorcontrib>Zapata, Ricardo A.</creatorcontrib><creatorcontrib>Rendón, Juan C.</creatorcontrib><creatorcontrib>Medina, Camilo Montoya</creatorcontrib><creatorcontrib>Escobar, José J.</creatorcontrib><creatorcontrib>Tobón, Marcela P.</creatorcontrib><creatorcontrib>Colorado, Maria F.</creatorcontrib><creatorcontrib>Vargas, Alberto R.</creatorcontrib><creatorcontrib>Uribe, Juan D.</creatorcontrib><creatorcontrib>Villegas, Alejandro Londoño</creatorcontrib><title>Twenty-Five Years of Lung Transplantation in Medellín: Overcoming the Challenges of an Emerging Country</title><title>Seminars in thoracic and cardiovascular surgery</title><addtitle>Semin Thorac Cardiovasc Surg</addtitle><description>The first successful lung transplant in Colombia was performed on October 28, 1997 in Medellín by Alberto Villegas Hernández at the “Clínica Cardiovascular Santa María” today called the Cardio VID Clinic. Here we present both survival outcomes and characteristics of the oldest and most experienced lung transplant program in Colombia. We conducted a retrospective study of all patients taken to lung transplantation at the Cardio VID Clinic in Medellín, Colombia from October 1997 to October 2022. Patient information from our institutional database and transplant archives were retrieved and reviewed. From October 1997 to October 2022, a total of 153 patients underwent orthotopic lung transplantation at our institution in Medellín, Colombia. Mean recipient age was 48 ± 13 years, the youngest patient was 15 years old and the oldest patient was 73 years old at the time of transplant. Seventy-four (48.4%) patients were men and seventy-nine (51.6%) were women. Uncensored lung transplant survival in Medellin at 1 month, 1 year, 5 years, and 10 years were 68%, 50%, 31%, and 12%, respectively. Although health care coverage in Colombia reaches nearly 100%, socioeconomic hurdles during post-transplant care, nonreturning patients, infections, and traumatic donor deaths lead to high mortality rates. Due to these factors, establishing successful and sustainable lung transplant programs in these settings is challenging.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Colombia</subject><subject>Developing Countries</subject><subject>Female</subject><subject>History, 21st Century</subject><subject>Humans</subject><subject>Lung Diseases - diagnosis</subject><subject>Lung Diseases - mortality</subject><subject>Lung Diseases - surgery</subject><subject>Lung transplantation</subject><subject>Lung Transplantation - adverse effects</subject><subject>Lung Transplantation - mortality</subject><subject>Male</subject><subject>Medellín</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Survival</subject><subject>Time Factors</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>1043-0679</issn><issn>1532-9488</issn><issn>1532-9488</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkMmOEzEQhi0EYhZ4BJCPXDq4vPTCBaFoZkAKmks4cLLc7urEUbc72O6M8lA8BS-GQwJXpJKqpPr-Wn5C3gBbAFPi_W4RcUz2EBeccbFgORg8I9egBC8aWdfPc82kKFhZNVfkJsYdYxwqIV6SK1FBKUHKa7JdP6FPx-LeHZB-RxMinXq6mv2GroPxcT8Yn0xyk6fO06_Y4TD8-uk_0McDBjuNLoNpi3S5NcOAfoN_9MbTuxHD5tRdTrNP4fiKvOjNEPH1Jd-Sb_d36-XnYvX48GX5aVVYASIVEkTTGoZQK8V71kluKuxKxBZNayoFipmy56XhUsqqFra2rITStGAkWGjELXl3nrsP048ZY9KjizZfbTxOc9S8Bq5Y2XCVUXVGbZhiDNjrfXCjCUcNTJ9M1jt9MVmfTNYsB4Ose3tZMbcjdv9Uf13NwMczgPnRg8Ogo3XoLXYuoE26m9x_VvwGlqqRjg</recordid><startdate>2024</startdate><enddate>2024</enddate><creator>Vinck, Eric E.</creator><creator>Zapata, Ricardo A.</creator><creator>Rendón, Juan C.</creator><creator>Medina, Camilo Montoya</creator><creator>Escobar, José J.</creator><creator>Tobón, Marcela P.</creator><creator>Colorado, Maria F.</creator><creator>Vargas, Alberto R.</creator><creator>Uribe, Juan D.</creator><creator>Villegas, Alejandro Londoño</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-9728-3910</orcidid></search><sort><creationdate>2024</creationdate><title>Twenty-Five Years of Lung Transplantation in Medellín: Overcoming the Challenges of an Emerging Country</title><author>Vinck, Eric E. ; Zapata, Ricardo A. ; Rendón, Juan C. ; Medina, Camilo Montoya ; Escobar, José J. ; Tobón, Marcela P. ; Colorado, Maria F. ; Vargas, Alberto R. ; Uribe, Juan D. ; Villegas, Alejandro Londoño</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c313t-4139ba0e18552f0d42a7ed6eebeaba75150a6f26a2444783c8c0616ab1a41c193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Colombia</topic><topic>Developing Countries</topic><topic>Female</topic><topic>History, 21st Century</topic><topic>Humans</topic><topic>Lung Diseases - diagnosis</topic><topic>Lung Diseases - mortality</topic><topic>Lung Diseases - surgery</topic><topic>Lung transplantation</topic><topic>Lung Transplantation - adverse effects</topic><topic>Lung Transplantation - mortality</topic><topic>Male</topic><topic>Medellín</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Survival</topic><topic>Time Factors</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Vinck, Eric E.</creatorcontrib><creatorcontrib>Zapata, Ricardo A.</creatorcontrib><creatorcontrib>Rendón, Juan C.</creatorcontrib><creatorcontrib>Medina, Camilo Montoya</creatorcontrib><creatorcontrib>Escobar, José J.</creatorcontrib><creatorcontrib>Tobón, Marcela P.</creatorcontrib><creatorcontrib>Colorado, Maria F.</creatorcontrib><creatorcontrib>Vargas, Alberto R.</creatorcontrib><creatorcontrib>Uribe, Juan D.</creatorcontrib><creatorcontrib>Villegas, Alejandro Londoño</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Seminars in thoracic and cardiovascular surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Vinck, Eric E.</au><au>Zapata, Ricardo A.</au><au>Rendón, Juan C.</au><au>Medina, Camilo Montoya</au><au>Escobar, José J.</au><au>Tobón, Marcela P.</au><au>Colorado, Maria F.</au><au>Vargas, Alberto R.</au><au>Uribe, Juan D.</au><au>Villegas, Alejandro Londoño</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Twenty-Five Years of Lung Transplantation in Medellín: Overcoming the Challenges of an Emerging Country</atitle><jtitle>Seminars in thoracic and cardiovascular surgery</jtitle><addtitle>Semin Thorac Cardiovasc Surg</addtitle><date>2024</date><risdate>2024</risdate><volume>36</volume><issue>3</issue><spage>369</spage><epage>375</epage><pages>369-375</pages><issn>1043-0679</issn><issn>1532-9488</issn><eissn>1532-9488</eissn><abstract>The first successful lung transplant in Colombia was performed on October 28, 1997 in Medellín by Alberto Villegas Hernández at the “Clínica Cardiovascular Santa María” today called the Cardio VID Clinic. Here we present both survival outcomes and characteristics of the oldest and most experienced lung transplant program in Colombia. We conducted a retrospective study of all patients taken to lung transplantation at the Cardio VID Clinic in Medellín, Colombia from October 1997 to October 2022. Patient information from our institutional database and transplant archives were retrieved and reviewed. From October 1997 to October 2022, a total of 153 patients underwent orthotopic lung transplantation at our institution in Medellín, Colombia. Mean recipient age was 48 ± 13 years, the youngest patient was 15 years old and the oldest patient was 73 years old at the time of transplant. Seventy-four (48.4%) patients were men and seventy-nine (51.6%) were women. Uncensored lung transplant survival in Medellin at 1 month, 1 year, 5 years, and 10 years were 68%, 50%, 31%, and 12%, respectively. Although health care coverage in Colombia reaches nearly 100%, socioeconomic hurdles during post-transplant care, nonreturning patients, infections, and traumatic donor deaths lead to high mortality rates. Due to these factors, establishing successful and sustainable lung transplant programs in these settings is challenging.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>37164144</pmid><doi>10.1053/j.semtcvs.2023.03.001</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-9728-3910</orcidid></addata></record> |
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subjects | Adolescent Adult Aged Colombia Developing Countries Female History, 21st Century Humans Lung Diseases - diagnosis Lung Diseases - mortality Lung Diseases - surgery Lung transplantation Lung Transplantation - adverse effects Lung Transplantation - mortality Male Medellín Middle Aged Retrospective Studies Risk Factors Survival Time Factors Treatment Outcome Young Adult |
title | Twenty-Five Years of Lung Transplantation in Medellín: Overcoming the Challenges of an Emerging Country |
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