Porcine epidemic diarrhea virus (PEDV) ORF3 protein inhibits cellular type I interferon signaling through down-regulating proteins expression in RLRs-mediated pathway

Porcine epidemic diarrhea virus (PEDV) is an entero-pathogenic coronavirus, which belongs to the genus Alphacoronavirus in the family Coronaviridae, causing lethal watery diarrhea in piglets. Previous studies have shown that PEDV has developed an antagonistic mechanism by which it evades the antivir...

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Veröffentlicht in:	Research in veterinary science 2023-06, Vol.159, p.146-159
Hauptverfasser:	Zheng, Liang, Liu, Hongxian, Tian, Zhipiao, Kay, Matthew, Wang, Hongyu, Cheng, Lixin, Xia, Wenlong, Zhang, Jiankang, Wang, Wenling, Cao, Hongwei, Xu, Xiaojuan, Gao, Zhenqiu, Geng, Rongqing, Wu, Zhijun, Zhang, Hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral immunity Coronavirus Infections - veterinary Interferon Type I - metabolism Open Reading Frames ORF3 protein Porcine epidemic diarrhea virus Porcine epidemic diarrhea virus - genetics RLRs-mediated pathway Signal Transduction Swine Swine Diseases Type I interferon
Online-Zugang:	Volltext
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