Synthesis of Pogostone‐Inspired Dehydroacetic Acid Derivatives and Their Antifungal Activity against Sclerotinia sclerotiorum (Lib.) de Bary

In an effort to exploit the natural antifungal pogostone, its simplified scaffold dehydroacetic acid (DHA) was used as a lead compound to semi‐synthesize 56 DHA derivatives (I1–48, II, III, and IV1–6). Among them, compound IV4 exhibited the most potent antifungal activity with 11.0 μM EC50 against m...

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