Zinc (Zn) and adipose-derived mesenchymal stem cells (AD-MSCs) on MPTP-induced Parkinson’s disease model: A comparative evaluation of behavioral and immunohistochemical results

Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons and sustained neuroinflammation due to microglial activation. Adipose tissue-derived mesenchymal stem cells (AD-MSCs) secrete neuroprotective factors to prevent neuronal damage. Furthermore, Zn regulates stem cell prolifer...

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Veröffentlicht in:	Neurotoxicology (Park Forest South) 2023-07, Vol.97, p.1-11
Hauptverfasser:	Yildirim, Sendegul, Oylumlu, Ece, Ozkan, Ayse, Sinen, Osman, Bulbul, Mehmet, Goksu, Ethem Taner, Ertosun, Mustafa Gokhan, Tanriover, Gamze
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine - pharmacology AD-MSC Animals Anti-inflammatory response Brain-Derived Neurotrophic Factor - metabolism Disease Models, Animal Dopaminergic neuron Dopaminergic Neurons Male Mesenchymal Stem Cells - metabolism Mice Mice, Inbred C57BL Neuroprotective Agents - metabolism Neuroprotective Agents - pharmacology Parkinson Disease - metabolism Parkinson Disease - therapy Parkinson’s disease Zinc - metabolism
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