A New Powder Dressing for Management of Chronic Venous Ulcers
A new powder dressing (TPD) is a methacrylate-based powder formulation that transforms in situ into a shape-retentive matrix upon hydration to create optimum moist wound healing conditions. The following randomized, controlled, clinical study aimed to evaluate the role of TPD in the management of ch...
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| Veröffentlicht in: | Dermatologic surgery 2023-07, Vol.49 (7), p.664-668 |
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| container_title | Dermatologic surgery |
| container_volume | 49 |
| creator | Mahmood, Barakat Abdelreheem ElSayed, Emad Hussein Abd Elghany, Salah M. Elnaggar, Dina Farouk Youssef, Hoda A. A. Abdelmaksoud, Saber M. |
| description | A new powder dressing (TPD) is a methacrylate-based powder formulation that transforms in situ into a shape-retentive matrix upon hydration to create optimum moist wound healing conditions. The following randomized, controlled, clinical study aimed to evaluate the role of TPD in the management of chronic venous ulcers (CVU).
The randomized controlled prospective study enrolled 60 CVU patients. After randomization, patients in the treatment group ( n = 30) were treated with TPD, whereas those in the control group ( n = 30) received conventional compression dressing therapy.
After treatment, patients in the TPD group had significantly higher rates of complete ulcer healing at 12 weeks (43.3% vs 10.0%, p = .004) and 24 weeks (86.7% vs 40.0%, p = .001) when compared with conventional dressing group. Moreover, patients in the TP dressing group had significantly shorter time to complete ulcer healing [mean (95% CI): 16.7 (14.1-19.3) versus 37.0 (30.8-43.2) weeks, p = .001]. In addition, patients in the TPD group had significantly fewer number of dressings, less severe pain after dressing, and lower need for systemic analgesics.
Use of TPD in management of CVUs was associated with significantly higher healing rates, shorter duration to healing, and lower pain. |
| doi_str_mv | 10.1097/DSS.0000000000003812 |
| format | Article |
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The randomized controlled prospective study enrolled 60 CVU patients. After randomization, patients in the treatment group ( n = 30) were treated with TPD, whereas those in the control group ( n = 30) received conventional compression dressing therapy.
After treatment, patients in the TPD group had significantly higher rates of complete ulcer healing at 12 weeks (43.3% vs 10.0%, p = .004) and 24 weeks (86.7% vs 40.0%, p = .001) when compared with conventional dressing group. Moreover, patients in the TP dressing group had significantly shorter time to complete ulcer healing [mean (95% CI): 16.7 (14.1-19.3) versus 37.0 (30.8-43.2) weeks, p = .001]. In addition, patients in the TPD group had significantly fewer number of dressings, less severe pain after dressing, and lower need for systemic analgesics.
Use of TPD in management of CVUs was associated with significantly higher healing rates, shorter duration to healing, and lower pain.</description><identifier>ISSN: 1076-0512</identifier><identifier>EISSN: 1524-4725</identifier><identifier>DOI: 10.1097/DSS.0000000000003812</identifier><identifier>PMID: 37134230</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins</publisher><subject>Bandages ; Humans ; Pain ; Powders - therapeutic use ; Prospective Studies ; Ulcer ; Varicose Ulcer - therapy</subject><ispartof>Dermatologic surgery, 2023-07, Vol.49 (7), p.664-668</ispartof><rights>Lippincott Williams & Wilkins</rights><rights>Copyright © 2023 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3017-ce5198604f1a5c1a2544a3281314872cc50df453069a4b676d922d7a2ef210d23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37134230$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mahmood, Barakat Abdelreheem</creatorcontrib><creatorcontrib>ElSayed, Emad Hussein</creatorcontrib><creatorcontrib>Abd Elghany, Salah M.</creatorcontrib><creatorcontrib>Elnaggar, Dina Farouk</creatorcontrib><creatorcontrib>Youssef, Hoda A. A.</creatorcontrib><creatorcontrib>Abdelmaksoud, Saber M.</creatorcontrib><title>A New Powder Dressing for Management of Chronic Venous Ulcers</title><title>Dermatologic surgery</title><addtitle>Dermatol Surg</addtitle><description>A new powder dressing (TPD) is a methacrylate-based powder formulation that transforms in situ into a shape-retentive matrix upon hydration to create optimum moist wound healing conditions. The following randomized, controlled, clinical study aimed to evaluate the role of TPD in the management of chronic venous ulcers (CVU).
The randomized controlled prospective study enrolled 60 CVU patients. After randomization, patients in the treatment group ( n = 30) were treated with TPD, whereas those in the control group ( n = 30) received conventional compression dressing therapy.
After treatment, patients in the TPD group had significantly higher rates of complete ulcer healing at 12 weeks (43.3% vs 10.0%, p = .004) and 24 weeks (86.7% vs 40.0%, p = .001) when compared with conventional dressing group. Moreover, patients in the TP dressing group had significantly shorter time to complete ulcer healing [mean (95% CI): 16.7 (14.1-19.3) versus 37.0 (30.8-43.2) weeks, p = .001]. In addition, patients in the TPD group had significantly fewer number of dressings, less severe pain after dressing, and lower need for systemic analgesics.
Use of TPD in management of CVUs was associated with significantly higher healing rates, shorter duration to healing, and lower pain.</description><subject>Bandages</subject><subject>Humans</subject><subject>Pain</subject><subject>Powders - therapeutic use</subject><subject>Prospective Studies</subject><subject>Ulcer</subject><subject>Varicose Ulcer - therapy</subject><issn>1076-0512</issn><issn>1524-4725</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkMlOw0AMhkcIRNneAKE5ckmxPTOZ5MChatkkNonlGg0ThxbSBGZaVbw9qcomfLEt_f5s_0LsI_QRcns0urvrw59QGdKa2EJDOtGWzHpXg00TMEg9sR3jCwBSrmBT9JRFpUnBljgeyGteyNt2UXKQo8AxTppnWbVBXrnGPfOUm5lsKzkch7aZePnITTuP8qH2HOKu2KhcHXnvK--Ih9OT--F5cnlzdjEcXCZeAdrEs8E8S0FX6IxHR0ZrpyhDhTqz5L2BstJGQZo7_ZTatMyJSuuIK0IoSe2IwxX3LbTvc46zYjqJnuvaNdxdU1AGudEW0XZSvZL60MYYuCrewmTqwkeBUCyNKzrjiv_GdWMHXxvmT1Muf4a-nfrlLtp61r3-Ws8XHIoxu3o2XvI0WcoSgk5suzZZoq36BHC-dR8</recordid><startdate>20230701</startdate><enddate>20230701</enddate><creator>Mahmood, Barakat Abdelreheem</creator><creator>ElSayed, Emad Hussein</creator><creator>Abd Elghany, Salah M.</creator><creator>Elnaggar, Dina Farouk</creator><creator>Youssef, Hoda A. A.</creator><creator>Abdelmaksoud, Saber M.</creator><general>Lippincott Williams & Wilkins</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20230701</creationdate><title>A New Powder Dressing for Management of Chronic Venous Ulcers</title><author>Mahmood, Barakat Abdelreheem ; ElSayed, Emad Hussein ; Abd Elghany, Salah M. ; Elnaggar, Dina Farouk ; Youssef, Hoda A. A. ; Abdelmaksoud, Saber M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3017-ce5198604f1a5c1a2544a3281314872cc50df453069a4b676d922d7a2ef210d23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Bandages</topic><topic>Humans</topic><topic>Pain</topic><topic>Powders - therapeutic use</topic><topic>Prospective Studies</topic><topic>Ulcer</topic><topic>Varicose Ulcer - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mahmood, Barakat Abdelreheem</creatorcontrib><creatorcontrib>ElSayed, Emad Hussein</creatorcontrib><creatorcontrib>Abd Elghany, Salah M.</creatorcontrib><creatorcontrib>Elnaggar, Dina Farouk</creatorcontrib><creatorcontrib>Youssef, Hoda A. A.</creatorcontrib><creatorcontrib>Abdelmaksoud, Saber M.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Dermatologic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mahmood, Barakat Abdelreheem</au><au>ElSayed, Emad Hussein</au><au>Abd Elghany, Salah M.</au><au>Elnaggar, Dina Farouk</au><au>Youssef, Hoda A. A.</au><au>Abdelmaksoud, Saber M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A New Powder Dressing for Management of Chronic Venous Ulcers</atitle><jtitle>Dermatologic surgery</jtitle><addtitle>Dermatol Surg</addtitle><date>2023-07-01</date><risdate>2023</risdate><volume>49</volume><issue>7</issue><spage>664</spage><epage>668</epage><pages>664-668</pages><issn>1076-0512</issn><eissn>1524-4725</eissn><abstract>A new powder dressing (TPD) is a methacrylate-based powder formulation that transforms in situ into a shape-retentive matrix upon hydration to create optimum moist wound healing conditions. The following randomized, controlled, clinical study aimed to evaluate the role of TPD in the management of chronic venous ulcers (CVU).
The randomized controlled prospective study enrolled 60 CVU patients. After randomization, patients in the treatment group ( n = 30) were treated with TPD, whereas those in the control group ( n = 30) received conventional compression dressing therapy.
After treatment, patients in the TPD group had significantly higher rates of complete ulcer healing at 12 weeks (43.3% vs 10.0%, p = .004) and 24 weeks (86.7% vs 40.0%, p = .001) when compared with conventional dressing group. Moreover, patients in the TP dressing group had significantly shorter time to complete ulcer healing [mean (95% CI): 16.7 (14.1-19.3) versus 37.0 (30.8-43.2) weeks, p = .001]. In addition, patients in the TPD group had significantly fewer number of dressings, less severe pain after dressing, and lower need for systemic analgesics.
Use of TPD in management of CVUs was associated with significantly higher healing rates, shorter duration to healing, and lower pain.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins</pub><pmid>37134230</pmid><doi>10.1097/DSS.0000000000003812</doi><tpages>5</tpages></addata></record> |
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| source | MEDLINE; Journals@Ovid Complete |
| subjects | Bandages Humans Pain Powders - therapeutic use Prospective Studies Ulcer Varicose Ulcer - therapy |
| title | A New Powder Dressing for Management of Chronic Venous Ulcers |
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