Cytoreductive surgery for advanced epithelial ovarian cancer in the poly(ADP-ribose) polymerase inhibitors era—Is it time for a new paradigm shift? A systematic review and meta-analysis

In patients with newly diagnosed advanced high-grade serous and endometrioid epithelial ovarian cancer (EOC) first-line maintenance therapy with poly(ADP-ribose) polymerase inhibitors (PARPi) tremendously improved progression-free survival (PFS). Yet, data on the effect of PARPi in proportion to pos...

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Veröffentlicht in:	European journal of cancer (1990) 2023-07, Vol.187, p.77-86
Hauptverfasser:	Peters, Inge T.A., Marchetti, Claudia, De Palma, Antonella, Giannarelli, Diana, Carcagnì, Antonella, Scambia, Giovanni, Fagotti, Anna
Format:	Artikel
Sprache:	eng
Schlagworte:	Carcinoma, Ovarian Epithelial - drug therapy Carcinoma, Ovarian Epithelial - surgery Cytoreduction Surgical Procedures Cytoreductive surgery Epithelial ovarian cancer Female Humans Ovarian Neoplasms - drug therapy Ovarian Neoplasms - surgery PARP inhibitors Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use Postoperative residual disease Progression-Free Survival
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