Evaluation of haematological, serum biochemical and oxidative stress parameters in cattle naturally infected with lumpy skin disease virus
Lumpy skin disease (LSD) is a vector-borne viral transboundary disease of cattle caused by the LSD virus (LSDV). Despite investigations on clinical and outbreak features of LSDV, information on disease pathogenesis and alternative changes in blood parameters are scarce. Keeping this in view, the cur...
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| Veröffentlicht in: | Tropical animal health and production 2023-06, Vol.55 (3), p.184-184, Article 184 |
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| creator | Ul-Rahman, Aziz Shahid, Muhammad Furqan Iqbal, Muhammad Zahid Channa, Aijaz Ali Rasheed, Majeeda Adnan, Muhammad Mahmood, Rauf Ishaq, Hafiz Muhammad Khera, Hafeez ur Rehman Ali Hussain, Kashif Raza, Muhammad Asif |
| description | Lumpy skin disease (LSD) is a vector-borne viral transboundary disease of cattle caused by the LSD virus (LSDV). Despite investigations on clinical and outbreak features of LSDV, information on disease pathogenesis and alternative changes in blood parameters are scarce. Keeping this in view, the current study was designed to determine haematological, serum biochemical, and oxidative stress parameters in naturally infected cattle with LSDV during the recent surge of outbreaks in Punjab, Pakistan. A total of 35 blood samples was collected from polymerase chain reaction-confirmed LSDV-infected cattle for assessment of all parameters. The haematological examination of blood samples showed a significant reduction (
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| doi_str_mv | 10.1007/s11250-023-03608-1 |
| format | Article |
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p
< 0.05) in different variables of erythrogram and leucogram. On the other hand, differences between levels of various serum biochemical parameters with the significant increase in levels of alkaline phosphatase, serum alanine aminotransferase, aspartate aminotransferase, and blood urea nitrogen were observed in LSDV naturally infected cattle. Moreover, malondialdehyde levels for lipid peroxidation and nitrate concentration were markedly elevated whereas glutathione S-transferase fluorescent and serum superoxide dismutase enzymes showed a decrease in levels. The current study suggests that alternations in haematological and serum biochemical parameters following LSDV infection stimulate oxidative stress and such findings may be useful for early and rapid diagnosis and improvement in the treatment strategy of the disease.</description><identifier>ISSN: 0049-4747</identifier><identifier>EISSN: 1573-7438</identifier><identifier>DOI: 10.1007/s11250-023-03608-1</identifier><identifier>PMID: 37129711</identifier><language>eng</language><publisher>Dordrecht: Springer Netherlands</publisher><subject>Alanine ; Alanine transaminase ; Alkaline Phosphatase ; Alternations ; Animals ; Aspartate aminotransferase ; Aspartate Aminotransferases ; aspartate transaminase ; Biochemistry ; Biomedical and Life Sciences ; Blood ; blood serum ; Cattle ; Cattle Diseases - epidemiology ; Disease Outbreaks - veterinary ; Epidemics ; Fluorescence ; Glutathione ; Glutathione transferase ; Hematology ; Life Sciences ; Lipid peroxidation ; Lipids ; Lumpy skin disease ; Lumpy Skin Disease - epidemiology ; Lumpy skin disease virus ; Lumpy skin disease virus - genetics ; malondialdehyde ; Medical diagnosis ; nitrates ; Outbreaks ; Oxidative stress ; Pakistan ; Parameters ; Pathogenesis ; Peroxidation ; Polymerase chain reaction ; Polymerase Chain Reaction - veterinary ; Regular Articles ; Skin diseases ; Superoxide dismutase ; Transaminases ; Urea ; urea nitrogen ; Veterinary Medicine/Veterinary Science ; Viral infections ; Viruses ; Zoology</subject><ispartof>Tropical animal health and production, 2023-06, Vol.55 (3), p.184-184, Article 184</ispartof><rights>The Author(s), under exclusive licence to Springer Nature B.V. 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. The Author(s), under exclusive licence to Springer Nature B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-a7a34132b9e04a3c417dc35da37fb4e6d4000cf91f1b9abc26c6679d5439b6983</citedby><cites>FETCH-LOGICAL-c408t-a7a34132b9e04a3c417dc35da37fb4e6d4000cf91f1b9abc26c6679d5439b6983</cites><orcidid>0000-0002-3342-4462</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s11250-023-03608-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s11250-023-03608-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51298</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37129711$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ul-Rahman, Aziz</creatorcontrib><creatorcontrib>Shahid, Muhammad Furqan</creatorcontrib><creatorcontrib>Iqbal, Muhammad Zahid</creatorcontrib><creatorcontrib>Channa, Aijaz Ali</creatorcontrib><creatorcontrib>Rasheed, Majeeda</creatorcontrib><creatorcontrib>Adnan, Muhammad</creatorcontrib><creatorcontrib>Mahmood, Rauf</creatorcontrib><creatorcontrib>Ishaq, Hafiz Muhammad</creatorcontrib><creatorcontrib>Khera, Hafeez ur Rehman Ali</creatorcontrib><creatorcontrib>Hussain, Kashif</creatorcontrib><creatorcontrib>Raza, Muhammad Asif</creatorcontrib><title>Evaluation of haematological, serum biochemical and oxidative stress parameters in cattle naturally infected with lumpy skin disease virus</title><title>Tropical animal health and production</title><addtitle>Trop Anim Health Prod</addtitle><addtitle>Trop Anim Health Prod</addtitle><description>Lumpy skin disease (LSD) is a vector-borne viral transboundary disease of cattle caused by the LSD virus (LSDV). Despite investigations on clinical and outbreak features of LSDV, information on disease pathogenesis and alternative changes in blood parameters are scarce. Keeping this in view, the current study was designed to determine haematological, serum biochemical, and oxidative stress parameters in naturally infected cattle with LSDV during the recent surge of outbreaks in Punjab, Pakistan. A total of 35 blood samples was collected from polymerase chain reaction-confirmed LSDV-infected cattle for assessment of all parameters. The haematological examination of blood samples showed a significant reduction (
p
< 0.05) in different variables of erythrogram and leucogram. On the other hand, differences between levels of various serum biochemical parameters with the significant increase in levels of alkaline phosphatase, serum alanine aminotransferase, aspartate aminotransferase, and blood urea nitrogen were observed in LSDV naturally infected cattle. Moreover, malondialdehyde levels for lipid peroxidation and nitrate concentration were markedly elevated whereas glutathione S-transferase fluorescent and serum superoxide dismutase enzymes showed a decrease in levels. The current study suggests that alternations in haematological and serum biochemical parameters following LSDV infection stimulate oxidative stress and such findings may be useful for early and rapid diagnosis and improvement in the treatment strategy of the disease.</description><subject>Alanine</subject><subject>Alanine transaminase</subject><subject>Alkaline Phosphatase</subject><subject>Alternations</subject><subject>Animals</subject><subject>Aspartate aminotransferase</subject><subject>Aspartate Aminotransferases</subject><subject>aspartate transaminase</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Blood</subject><subject>blood serum</subject><subject>Cattle</subject><subject>Cattle Diseases - epidemiology</subject><subject>Disease Outbreaks - veterinary</subject><subject>Epidemics</subject><subject>Fluorescence</subject><subject>Glutathione</subject><subject>Glutathione transferase</subject><subject>Hematology</subject><subject>Life Sciences</subject><subject>Lipid peroxidation</subject><subject>Lipids</subject><subject>Lumpy skin disease</subject><subject>Lumpy Skin Disease - epidemiology</subject><subject>Lumpy skin disease virus</subject><subject>Lumpy skin disease virus - genetics</subject><subject>malondialdehyde</subject><subject>Medical diagnosis</subject><subject>nitrates</subject><subject>Outbreaks</subject><subject>Oxidative stress</subject><subject>Pakistan</subject><subject>Parameters</subject><subject>Pathogenesis</subject><subject>Peroxidation</subject><subject>Polymerase chain reaction</subject><subject>Polymerase Chain Reaction - veterinary</subject><subject>Regular Articles</subject><subject>Skin diseases</subject><subject>Superoxide dismutase</subject><subject>Transaminases</subject><subject>Urea</subject><subject>urea nitrogen</subject><subject>Veterinary Medicine/Veterinary Science</subject><subject>Viral infections</subject><subject>Viruses</subject><subject>Zoology</subject><issn>0049-4747</issn><issn>1573-7438</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkcFu1DAQhi0EotvCC3BAlrhwIGDHjp0cUVUoUiUucI4mzqTr4sSLx1nYV-CpcbsFJA5wsjT-_n80-hh7JsVrKYR9Q1LWjahErSqhjGgr-YBtZGNVZbVqH7KNELqrtNX2hJ0S3QhRYq15zE6UlXVnpdywHxd7CCtkHxceJ74FnCHHEK-9g_CKE6Z15oOPbovz7YjDMvL43Y8lskdOOSER30GCGTMm4n7hDnIOyBfIa4IQDmU2ocs48m8-b3lY592B05dCjp4QCPnep5WesEcTBMKn9-8Z-_zu4tP5ZXX18f2H87dXldOizRVYUFqqeuhQaFBOSzs61Yyg7DRoNKMWQripk5McOhhcbZwxthsbrbrBdK06Yy-PvbsUv65IuZ89OQwBFowr9Uo2ShqhdP1ftG5F27S2M7qgL_5Cb-KalnLIHaXr1pqmUPWRcikSJZz6XfIzpEMvRX8rtT9K7YvU_k5qL0vo-X31Osw4_o78slgAdQSofC3XmP7s_kftT5Uzrpg</recordid><startdate>20230601</startdate><enddate>20230601</enddate><creator>Ul-Rahman, Aziz</creator><creator>Shahid, Muhammad Furqan</creator><creator>Iqbal, Muhammad Zahid</creator><creator>Channa, Aijaz Ali</creator><creator>Rasheed, Majeeda</creator><creator>Adnan, Muhammad</creator><creator>Mahmood, Rauf</creator><creator>Ishaq, Hafiz Muhammad</creator><creator>Khera, Hafeez ur Rehman Ali</creator><creator>Hussain, Kashif</creator><creator>Raza, Muhammad Asif</creator><general>Springer Netherlands</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7T7</scope><scope>7U7</scope><scope>7U9</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>7S9</scope><scope>L.6</scope><orcidid>https://orcid.org/0000-0002-3342-4462</orcidid></search><sort><creationdate>20230601</creationdate><title>Evaluation of haematological, serum biochemical and oxidative stress parameters in cattle naturally infected with lumpy skin disease virus</title><author>Ul-Rahman, Aziz ; Shahid, Muhammad Furqan ; Iqbal, Muhammad Zahid ; Channa, Aijaz Ali ; Rasheed, Majeeda ; Adnan, Muhammad ; Mahmood, Rauf ; Ishaq, Hafiz Muhammad ; Khera, Hafeez ur Rehman Ali ; Hussain, Kashif ; Raza, Muhammad Asif</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c408t-a7a34132b9e04a3c417dc35da37fb4e6d4000cf91f1b9abc26c6679d5439b6983</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Alanine</topic><topic>Alanine transaminase</topic><topic>Alkaline Phosphatase</topic><topic>Alternations</topic><topic>Animals</topic><topic>Aspartate aminotransferase</topic><topic>Aspartate Aminotransferases</topic><topic>aspartate transaminase</topic><topic>Biochemistry</topic><topic>Biomedical and Life Sciences</topic><topic>Blood</topic><topic>blood serum</topic><topic>Cattle</topic><topic>Cattle Diseases - epidemiology</topic><topic>Disease Outbreaks - veterinary</topic><topic>Epidemics</topic><topic>Fluorescence</topic><topic>Glutathione</topic><topic>Glutathione transferase</topic><topic>Hematology</topic><topic>Life Sciences</topic><topic>Lipid peroxidation</topic><topic>Lipids</topic><topic>Lumpy skin disease</topic><topic>Lumpy Skin Disease - epidemiology</topic><topic>Lumpy skin disease virus</topic><topic>Lumpy skin disease virus - genetics</topic><topic>malondialdehyde</topic><topic>Medical diagnosis</topic><topic>nitrates</topic><topic>Outbreaks</topic><topic>Oxidative stress</topic><topic>Pakistan</topic><topic>Parameters</topic><topic>Pathogenesis</topic><topic>Peroxidation</topic><topic>Polymerase chain reaction</topic><topic>Polymerase Chain Reaction - veterinary</topic><topic>Regular Articles</topic><topic>Skin diseases</topic><topic>Superoxide dismutase</topic><topic>Transaminases</topic><topic>Urea</topic><topic>urea nitrogen</topic><topic>Veterinary Medicine/Veterinary Science</topic><topic>Viral infections</topic><topic>Viruses</topic><topic>Zoology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ul-Rahman, Aziz</creatorcontrib><creatorcontrib>Shahid, Muhammad Furqan</creatorcontrib><creatorcontrib>Iqbal, Muhammad Zahid</creatorcontrib><creatorcontrib>Channa, Aijaz Ali</creatorcontrib><creatorcontrib>Rasheed, Majeeda</creatorcontrib><creatorcontrib>Adnan, Muhammad</creatorcontrib><creatorcontrib>Mahmood, Rauf</creatorcontrib><creatorcontrib>Ishaq, Hafiz Muhammad</creatorcontrib><creatorcontrib>Khera, Hafeez ur Rehman Ali</creatorcontrib><creatorcontrib>Hussain, Kashif</creatorcontrib><creatorcontrib>Raza, Muhammad Asif</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - 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Despite investigations on clinical and outbreak features of LSDV, information on disease pathogenesis and alternative changes in blood parameters are scarce. Keeping this in view, the current study was designed to determine haematological, serum biochemical, and oxidative stress parameters in naturally infected cattle with LSDV during the recent surge of outbreaks in Punjab, Pakistan. A total of 35 blood samples was collected from polymerase chain reaction-confirmed LSDV-infected cattle for assessment of all parameters. The haematological examination of blood samples showed a significant reduction (
p
< 0.05) in different variables of erythrogram and leucogram. On the other hand, differences between levels of various serum biochemical parameters with the significant increase in levels of alkaline phosphatase, serum alanine aminotransferase, aspartate aminotransferase, and blood urea nitrogen were observed in LSDV naturally infected cattle. Moreover, malondialdehyde levels for lipid peroxidation and nitrate concentration were markedly elevated whereas glutathione S-transferase fluorescent and serum superoxide dismutase enzymes showed a decrease in levels. The current study suggests that alternations in haematological and serum biochemical parameters following LSDV infection stimulate oxidative stress and such findings may be useful for early and rapid diagnosis and improvement in the treatment strategy of the disease.</abstract><cop>Dordrecht</cop><pub>Springer Netherlands</pub><pmid>37129711</pmid><doi>10.1007/s11250-023-03608-1</doi><tpages>1</tpages><orcidid>https://orcid.org/0000-0002-3342-4462</orcidid></addata></record> |
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| ispartof | Tropical animal health and production, 2023-06, Vol.55 (3), p.184-184, Article 184 |
| issn | 0049-4747 1573-7438 |
| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Alanine Alanine transaminase Alkaline Phosphatase Alternations Animals Aspartate aminotransferase Aspartate Aminotransferases aspartate transaminase Biochemistry Biomedical and Life Sciences Blood blood serum Cattle Cattle Diseases - epidemiology Disease Outbreaks - veterinary Epidemics Fluorescence Glutathione Glutathione transferase Hematology Life Sciences Lipid peroxidation Lipids Lumpy skin disease Lumpy Skin Disease - epidemiology Lumpy skin disease virus Lumpy skin disease virus - genetics malondialdehyde Medical diagnosis nitrates Outbreaks Oxidative stress Pakistan Parameters Pathogenesis Peroxidation Polymerase chain reaction Polymerase Chain Reaction - veterinary Regular Articles Skin diseases Superoxide dismutase Transaminases Urea urea nitrogen Veterinary Medicine/Veterinary Science Viral infections Viruses Zoology |
| title | Evaluation of haematological, serum biochemical and oxidative stress parameters in cattle naturally infected with lumpy skin disease virus |
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