EIF4A3-induced circZFAND6 promotes breast cancer proliferation and metastasis through the miR-647/FASN axis

Circular RNAs (circRNAs) are important regulators in breast cancer progression. However, the underlying mechanism of circRNAs functions in breast cancer remain largely unclear. To investigate the circRNAs expression pattern in breast cancer, high-throughput circRNA microarray assay was used. The top...

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Veröffentlicht in:	Life sciences (1973) 2023-07, Vol.324, p.121745-121745, Article 121745
Hauptverfasser:	Huang, Xiaojia, Tan, Weige, Liu, Ziteng, Fu, Xiaoyan, Li, Zongyan, Lai, Shengqing, Li, Qian, Zhong, Xiaofang, Qu, Fanli, Zhang, Huayao, Li, Haiyan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Cell Line, Tumor Cell Movement - genetics Cell Proliferation - genetics circZFAND6 DEAD-box RNA Helicases - genetics EIF4A3 Eukaryotic Initiation Factor-4A - genetics Eukaryotic Initiation Factor-4A - metabolism FASN Fatty Acid Synthase, Type I - genetics Female Gene Expression Regulation, Neoplastic Humans Mice MicroRNAs - genetics MicroRNAs - metabolism miR-647 RNA, Circular - genetics
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