Brevetoxin induces a shift in the redox state of the proteome and unfolded protein response in human lymphoblast cells that can be alleviated with the acrolein scavenger MESNA

Human lymphoblast cells were treated with the marine algal toxin, brevetoxin-2 (PbTx-2), and its effects on the proteome were assessed by redox proteomics using cysteine reactive tandem mass tags (TMT). Additionally, cells were simultaneously treated with PbTx-2 and the antioxidant and acrolein scav...

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Veröffentlicht in:	Environmental toxicology and pharmacology 2023-06, Vol.100, p.104137-104137, Article 104137
Hauptverfasser:	Jobson, Jordan, Tsegay, Pawlos S., Beltran, Mayra Tabares, Taher, Eman A., Rein, Samuel R., Liu, Yuan, Rein, Kathleen S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Brevetoxin Oxidative stress Unfolded protein response ER stress Red tide Redox proteomics
Online-Zugang:	Volltext
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