Synthesis and anti-proliferative activity of dehydroabietinol derivatives bearing a triazole moiety

In search of more efficacious antitumor agents, a series of novel dehydroabietinol derivatives containing a triazole moiety was synthesized, and evaluated for cytotoxicity against four human cancer cell lines. Many exhibited superior cytotoxic profiles compared to the parent molecule, dehydroabietic...

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Veröffentlicht in:MedChemComm 2023-04, Vol.14 (4), p.68-691
Hauptverfasser: Zhu, Mingjun, Sun, Jinchuan, Wu, Yaju, Ma, Xianli, Lei, Fuhou, Li, Qian, Jiang, Caina, Li, Fangyao
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Sprache:eng
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