The signal conversion strategy using the lytic transglycosylase Cag4-double nanoporous gold co-catalysis for the rapid screening of drugs against Helicobacter pylori infection

The cag pathogenicity island (cagPAI) is the main virulence factor of gastric carcinoma induced by Helicobacter pylori (H. pylori). The lytic transglycosylase Cag4 is an important component that assists in the translocation of the bacterial oncoprotein CagA and maintains the peptidoglycan cycle. The...

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Veröffentlicht in:	Biosensors & bioelectronics 2023-08, Vol.233, p.115345-115345, Article 115345
Hauptverfasser:	Xiao, Sa, Zhang, Lei, Wang, Xiaolei, Li, Wenjuan, Wang, Xia
Format:	Artikel
Sprache:	eng
Schlagworte:	Allosteric regulation Antigens, Bacterial Bacterial Proteins Biosensing Techniques Cag pathogenicity island Chitosan Escherichia coli Helicobacter Infections - microbiology Helicobacter pylori Humans Lytic transglycosylases Molecular Docking Simulation Nanopores
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