Glucose metabolic reprogramming and modulation in glycerol biosynthesis regulates drug resistance in clinical isolates of Candida

The study is aimed at understanding the novel molecular mechanisms governing drug resistance in the opportunistic fungi belonging to the genus Candida. This is a multipronged study wherein different assays like drug susceptibility and whole cell proteome analysis, stress tolerance assay, measurement...

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Veröffentlicht in:	Journal of applied microbiology 2023-05, Vol.134 (5)
Hauptverfasser:	Padder, Sajad Ahmad, Padder, Rayees Ahmad, Ramzan, Asiya, Bashir, Gulnaz, Tahir, Inayatullah, Rehman, Reiaz Ul, Shah, Abdul Haseeb
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate Antifungal Agents - pharmacology Candida - genetics Candida albicans Candida glabrata Drug Resistance, Fungal - genetics Glycerol Humans Microbial Sensitivity Tests NADP Reactive Oxygen Species
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