Nanosome-Mediated Delivery Of Hdac Inhibitors and Oxygen Molecules for the Transcriptional Reactivation of Latent Hiv-Infected Cd4 + T Cells

The treatment of human immunodeficiency virus (HIV) infection is notoriously difficult due to the ability of this virus to remain latent in the host's CD4 T cells. Histone deacetylases (HDACs) interfere with DNA transcription in HIV-infected hosts, resulting in viral latency. Therefore, HDAC in...

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Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2023-09, Vol.19 (37), p.e2301730-e2301730
Hauptverfasser:	Hong, Joohye, Choi, Yonghyun, Lee, Gahyun, Kim, Jiwon, Jang, Yeonwoo, Yoon, Cheol-Hee, Seo, Hyun Wook, Park, In-Kyu, Kang, Shin Hyuk, Choi, Jonghoon
Format:	Artikel
Sprache:	eng
Schlagworte:	Bilayers Binding Drug carriers Drug delivery systems HIV Human immunodeficiency virus Inhibitors Lymphocytes Nanotechnology Oxygen Peptides Phospholipids
Online-Zugang:	Volltext
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