Effect of a moderate CYP3A inducer efavirenz on the pharmacokinetics of fuzuloparib: An open-label, fixed sequence study in Chinese healthy male subjects

Summary To evaluate the potential drug-drug interaction (DDI), safety and tolerability of fuzuloparib co-administered with a moderate CYP3A inducer efavirenz in healthy male subjects. Eighteen healthy male subjects were enrolled in a single-center, single-arm, open-label, fixed-sequence study. Fuzul...

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Veröffentlicht in:Investigational new drugs 2023-04, Vol.41 (2), p.276-283
Hauptverfasser: Hu, Linlin, Dou, Ting, Sun, Qiuyue, Tang, Lu, Cai, Mingmin, Qian, Wei, Wang, Huiping
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Sprache:eng
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