The role of diet in shaping human gut microbiota

Gut microbiota plays a fundamental role within human health, and exerts key functions within the human body. Diet is one of the most powerful modulators of gut microbiota functions and composition. This complex interplay involves also the immune system and the intestinal barrier, highlighting the ce...

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Veröffentlicht in:Baillière's best practice & research. Clinical gastroenterology 2023-02, Vol.62-63, p.101828-101828, Article 101828
Hauptverfasser: Rinninella, Emanuele, Tohumcu, Ege, Raoul, Pauline, Fiorani, Marcello, Cintoni, Marco, Mele, Maria Cristina, Cammarota, Giovanni, Gasbarrini, Antonio, Ianiro, Gianluca
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container_title Baillière's best practice & research. Clinical gastroenterology
container_volume 62-63
creator Rinninella, Emanuele
Tohumcu, Ege
Raoul, Pauline
Fiorani, Marcello
Cintoni, Marco
Mele, Maria Cristina
Cammarota, Giovanni
Gasbarrini, Antonio
Ianiro, Gianluca
description Gut microbiota plays a fundamental role within human health, and exerts key functions within the human body. Diet is one of the most powerful modulators of gut microbiota functions and composition. This complex interplay involves also the immune system and the intestinal barrier, highlighting the central role of diet in the pathogenesis and treatment of multiple diseases. In this review article we will paint the landscape of the effects of specific dietary nutrients, and of the detrimental or beneficial outcomes of different dietary patterns, on the composition of human gut microbiota. Moreover, we will discuss the potential application of diet as a therapeutic modulator of gut microbiota, including cutting-edge ways of exploitation, including the use of dietary components as adjuvants to promote microbial engraftment after fecal microbiota transplantation, or personalized nutritional approaches, targeted to the patient microbiome.
doi_str_mv 10.1016/j.bpg.2023.101828
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Diet
Gastrointestinal Microbiome
Gut microbiota
Humans
Intestines
Microbiome
Microbiota
title The role of diet in shaping human gut microbiota
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