Icariin, the main prenylflavonoid of Epimedii Folium, ameliorated chronic kidney disease by modulating energy metabolism via AMPK activation

Epimedii Folium is a famous traditional Chinese medicine (TCM) widely used in classic formulas, Chinese patent drugs and health care products for treating kidney diseases. Therefore, we speculated that icariin, its main component, might also have a good therapeutic effect on chronic kidney disease (...

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Veröffentlicht in:	Journal of ethnopharmacology 2023-08, Vol.312, p.116543-116543, Article 116543
Hauptverfasser:	Zhao, Yudan, Yang, Wanyue, Zhang, Xin, Lv, Chongning, Lu, Jincai
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine AMP-Activated Protein Kinases - metabolism AMPK Animals Chronic kidney disease Energy Metabolism Fibrosis Icariin Kidney Male Metabolomics Rats Rats, Sprague-Dawley Renal Insufficiency, Chronic - chemically induced Renal Insufficiency, Chronic - drug therapy Renal Insufficiency, Chronic - metabolism
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