Human CCR6+ Th Cells Show Both an Extended Stable Gradient of Th17 Activity and Imprinted Plasticity

Th17 cells have been investigated in mice primarily for their contributions to autoimmune diseases. However, the pathways of differentiation of Th17 and related Th cells (type 17 cells) and the structure of the type 17 memory population in humans are not well understood; such understanding is critic...

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Veröffentlicht in:	The Journal of immunology (1950) 2023-06, Vol.210 (11), p.1700-1716
Hauptverfasser:	Singh, Satya P, Parween, Farhat, Edara, Nithin, Zhang, Hongwei H, Chen, Jinguo, Otaizo-Carrasquero, Francisco, Cheng, Debby, Oppenheim, Nicole A, Ransier, Amy, Zhu, Wenjun, Shamsaddini, Amirhossein, Gardina, Paul J, Darko, Samuel W, Singh, Tej Pratap, Douek, Daniel C, Myers, Timothy G, Farber, Joshua M
Format:	Artikel
Sprache:	eng
Schlagworte:	Autoimmune Diseases Cell Differentiation Humans Phenotype Receptors, CCR6 - genetics Th1 Cells - metabolism Th17 Cells
Online-Zugang:	Volltext
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