Comparison of the loci associated with HbA1c and blood glucose levels identified by a genome-wide association study in the Japanese population

Aims Hemoglobin A1c (HbA1c) levels are widely employed to diagnose diabetes. However, estimates of the heritability of HbA1c and glucose levels are different. Therefore, we explored HbA1c- and blood glucose-associated loci in a non-diabetic Japanese population. Methods We conducted a two-stage genom...

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Veröffentlicht in:	Diabetology International 2023-04, Vol.14 (2), p.188-198
Hauptverfasser:	Sakashita, Takuya, Nakamura, Yasuyuki, Sutoh, Yoichi, Shimizu, Atsushi, Hachiya, Tsuyoshi, Otsuka-Yamasaki, Yayoi, Takashima, Naoyuki, Kadota, Aya, Miura, Katsuyuki, Kita, Yoshikuni, Ikezaki, Hiroaki, Otonari, Jun, Tanaka, Keitaro, Shimanoe, Chisato, Koyama, Teruhide, Watanabe, Isao, Suzuki, Sadao, Nakagawa-Senda, Hiroko, Hishida, Asahi, Tamura, Takashi, Kato, Yasufumi, Okada, Rieko, Kuriki, Kiyonori, Katsuura-Kamano, Sakurako, Watanabe, Takeshi, Tanoue, Shiroh, Koriyama, Chihaya, Oze, Isao, Koyanagi, Yuriko N., Nakamura, Yohko, Kusakabe, Miho, Nakatochi, Masahiro, Momozawa, Yukihide, Wakai, Kenji, Matsuo, Keitaro
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood glucose Blood sugar Body mass index Comparative analysis Diabetes Diabetes mellitus Endocrinology Genetic aspects Genetic diversity Genetic research Genome-wide association studies Genomes Genomics Glucose Glycosylated hemoglobin Hemoglobin Heritability KCNQ1 protein Medicine Medicine & Public Health Metabolic Diseases Original Article Population studies Potassium channels (voltage-gated)
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