Synthesis and Evaluation of a Self-Adjuvanting Pseudomonal Vaccine Based on Major Outer Membrane Porin OprF Epitopes Formulated with Low-Toxicity QS-21-Containing Liposomes

Pseudomonas aeruginosa (PA) is a Gram-negative pathogen that the World Health Organization has ranked as a priority 1 (critical) threat. One potential prophylactic approach to preventing or reducing the incidence of PA would be development of a long sought-after vaccine. Both antibody and CD4+ T-cel...

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Veröffentlicht in:Bioconjugate chemistry 2023-05, Vol.34 (5), p.893-910
Hauptverfasser: Thanvi, Radhika, Nada, Shadia, Dissanayake, Ravindika, Vartak, Abhishek, Sebilleau, Chloé Olayinka, Alom, Nur-E, Prestwich, Erin G., Wall, Katherine A., Sucheck, Steven J.
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