Selected cannabis terpenes synergize with THC to produce increased CB1 receptor activation

[Display omitted] The cannabis plant exerts its pharmaceutical activity primarily by the binding of cannabinoids to two G protein-coupled cannabinoid receptors, CB1 and CB2. The role that cannabis terpenes play in this activation has been considered and debated repeatedly, based on only limited expe...

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Veröffentlicht in:	Biochemical pharmacology 2023-06, Vol.212, p.115548-115548, Article 115548
Hauptverfasser:	Raz, Noa, Eyal, Aharon M., Zeitouni, Dana Berneman, Hen-Shoval, Danielle, Davidson, Elyad M., Danieli, Aviel, Tauber, Merav, Ben-Chaim, Yair
Format:	Artikel
Sprache:	eng
Schlagworte:	Cannabinoid Receptor Agonists Cannabinoids - pharmacology Cannabinoids - therapeutic use Cannabis Cannabis - chemistry CB1 receptor Dronabinol - pharmacology Hallucinogens Receptor, Cannabinoid, CB1 Receptor, Cannabinoid, CB2 Terpenes Terpenes - pharmacology THC Xenopus oocytes
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