Changes in ventilation modes in the last decade and their impact on the prevalence of bronchopulmonary dysplasia in preterm infants

Background Less invasive forms of ventilation have evolved aiming to decrease bronchopulmonary dysplasia (BPD) morbidity. It is unclear whether changes in ventilation practices have been associated with improvements in respiratory outcomes. Objective To examine the changes in ventilation modes in preterm neonates between two periods during the last decade and their impact on BPD prevalence. Methods A retrospective chart review of very low birth weight infants and those born at less than 32 weeks gestation hospitalized during two periods: the years 2012–2013 and 2018–2019. The primary outcome was the prevalence of BPD. Study variables included the mode and duration of ventilation, duration of oxygen need, and perinatal clinical parameters. Results Four hundred eighty‐one infants were enrolled. Between the two study periods, a significant increase was observed in invasive (33%–47%, p = 0.002), and noninvasive ventilation rates (44%–72%, p