Pathogenetic Mechanisms of Mental Disorders: Endogenous Intoxication
The review describes the syndrome of endogenous intoxication in patients with mental disorders. Oxidative stress, middle-mass endotoxic molecules, impaired functional properties of serum albumin and albumin thiol groups, neurotrophic factors, and enzymes, including monoamine oxidase and semicarbazid...
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| Veröffentlicht in: | Biochemistry (Moscow) 2023-04, Vol.88 (4), p.491-501 |
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| creator | Uzbekov, Marat G. |
| description | The review describes the syndrome of endogenous intoxication in patients with mental disorders. Oxidative stress, middle-mass endotoxic molecules, impaired functional properties of serum albumin and albumin thiol groups, neurotrophic factors, and enzymes, including monoamine oxidase and semicarbazide-sensitive amine oxidase contribute to the development of endogenous intoxication. Possible pathogenetic mechanisms of the endogenous intoxication development in mental disorders and approaches to its treatment are discussed. |
| doi_str_mv | 10.1134/S0006297923040053 |
| format | Article |
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| subjects | Albumin Amine Oxidase (Copper-Containing) - metabolism Amine oxidase (flavin-containing) Antioxidants Apoptosis Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Brain research Care and treatment Development and progression Drunkenness (Criminal law) Enzymes Free radicals Humans Influence Intoxication Life Sciences Lipids Mental depression Mental Disorders Mental illness Metabolism Metabolites Microbiology Mitochondrial DNA Monoamine Oxidase Neurogenesis Neurotrophic factors Oxidase Oxidation Oxidative Stress Pathogenesis Physiological aspects Physiology Proteins Review Semicarbazide Semicarbazide-sensitive amine oxidase Serum Albumin |
| title | Pathogenetic Mechanisms of Mental Disorders: Endogenous Intoxication |
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