Two staged phase II clinical trial of Eribulin monotherapy in advanced or recurrent cervical cancer

Eribulin a microtubule targeting agent and analog of Halichondrin B, a natural product isolated from marine sponge H. okadai, has proven clinical efficacy in metastatic pretreated breast cancer and liposarcoma. We conducted a 2-stage Phase II study of eribulin in patients with advanced/recurrent cer...

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Veröffentlicht in:	Gynecologic oncology 2023-06, Vol.173, p.49-57
Hauptverfasser:	Garcia-Sayre, Jocelyn, Lin, Yvonne G., Matsuo, Koji, Tsao-Wei, Denice D., Mhawech-Fauceglia, Paulette, Louie, Stan, Dong, Tiange, Ciccone, Marcia A., Brunette-Masi, Laurie L., Pham, Huyen Q., Yessaian, Annie A., Groshen, Susan G., Facio, Grace, Aldana, Marissa, Muderspach, Laila I., Garcia, Agustin A., Roman, Lynda D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Combined Chemotherapy Protocols - adverse effects bcl-2-Associated X Protein - therapeutic use Biomarkers Breast Neoplasms - drug therapy Cervical cancer Chemotherapy Cisplatin - therapeutic use Female Humans Neoplasm Recurrence, Local - drug therapy Neoplasm Recurrence, Local - etiology Paclitaxel Treatment Outcome Uterine Cervical Neoplasms - drug therapy Uterine Cervical Neoplasms - etiology
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