Role of circular RNAs in osteoarthritis: update on pathogenesis and therapeutics

Osteoarthritis (OA) is a common and crippling joint disease characterized by cartilage degeneration, subchondral bone sclerosis, and synovitis. The main clinical manifestations of OA are chronic joint pain and impaired mobility, which seriously affect patient’s quality of life. Circular RNAs (circRN...

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Veröffentlicht in:	Molecular genetics and genomics : MGG 2023-07, Vol.298 (4), p.791-801
Hauptverfasser:	Wang, Hulin, Zhao, Junjie, Wang, Jin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Genetics and Genomics Apoptosis Arthralgia Arthritis Biochemistry Biomedical and Life Sciences Cartilage Cartilage diseases Chondrocytes Circular RNA Degeneration Extracellular matrix Human Genetics Joint diseases Life Sciences Microbial Genetics and Genomics Osteoarthritis Plant Genetics and Genomics Quality of life Review Sclerosis Subchondral bone Synovitis Synovium
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