Transient Receptor Potential (TRP) based polypharmacological combination stimulates energy expending phenotype to reverse HFD-induced obesity in mice

Obesity is a worldwide epidemic leading to decreased quality of life, higher medical expenses and significant morbidity. Enhancing energy expenditure and substrate utilization in adipose tissues through dietary constituents and polypharmacological approaches is gaining importance for the prevention...

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Veröffentlicht in:	Life sciences (1973) 2023-07, Vol.324, p.121704-121704, Article 121704
Hauptverfasser:	Kaur, Jasleen, Singh, Dhirendra Pratap, Kumar, Vijay, Kaur, Simranjit, Bhunia, Rupam Kumar, Kondepudi, Kanthi Kiran, Kuhad, Anurag, Bishnoi, Mahendra
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue, Brown - metabolism Adipose Tissue, White - metabolism Animals Brite Browning Capsaicin - metabolism Capsaicin - pharmacology Diet, High-Fat - adverse effects Energy expending Energy Metabolism Functional foods Menthol - metabolism Menthol - pharmacology Menthol - therapeutic use Mice Mice, Inbred C57BL Obesity Obesity - drug therapy Obesity - etiology Obesity - metabolism Phenotype Polypharmacology Quality of Life TRP
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