UHPLC‐Orbitrap‐Fusion‐TMS‐Based Metabolomics Study of Phenylpropionamides in the Seed of Cannabis sativa L. against Alzheimer's Disease

Phenylpropionamides in the seed of Cannabis sativa L. (PHS) have a protective effect on neuroinflammation and antioxidant activity. In this study, the UHPLC‐Orbitrap‐fusion‐TMS‐based metabolomics approach was used to analyze the serum samples and identify potential biomarkers in Streptozotocin (STZ)...

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Veröffentlicht in:	Chemistry & biodiversity 2023-05, Vol.20 (5), p.e202201047-n/a
Hauptverfasser:	Wu, Dan‐Dan, Liu, Yan, Guan, Wei, Pan, Juan, Kuang, Hai‐Xue, Yang, Bing‐You
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - chemically induced Alzheimer Disease - drug therapy Alzheimer's disease Animals Bile Acids and Salts Biomarkers Biosynthesis Cannabis Cannabis sativa Cannabis sativa L Chromatography, High Pressure Liquid Cysteamine Cysteine Cysteine dioxygenase Enzymes Inflammation Marijuana Metabolism Metabolomics Neurodegenerative diseases phenylpropionamides Rats Steroid 12-alpha-Hydroxylase Streptozocin Taurine Taurine - metabolism Taurine - pharmacology
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