Low dose acetyl salicylic acid (LDA) mediates epigenetic changes in preeclampsia placental mesenchymal stem cells similar to cells from healthy pregnancy

Preeclampsia (PE) affects 2–8% of all pregnancies, and is the leading cause of maternal and fetal morbidity and mortality. We reported on pathophysiological changes in placenta mesenchymal stem cells (P-MSCs) in PE. P-MSCs can be isolated from different layers of the placenta at the interface betwee...

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Veröffentlicht in:	Placenta (Eastbourne) 2023-06, Vol.137, p.49-58
Hauptverfasser:	Krishnamoorthy, Kaila, Sherman, Lauren S., Romagano, Matthew P., El Far, Markos, Etchegaray, Jean-Pierre, Williams, Shauna F., Rameshwar, Pranela
Format:	Artikel
Sprache:	eng
Schlagworte:	Aspirin - pharmacology Aspirin - therapeutic use Epigenesis, Genetic Female Humans Mesenchymal Stem Cells - metabolism Placenta - metabolism Pre-Eclampsia - metabolism Pregnancy Salicylic Acid - metabolism
Online-Zugang:	Volltext
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