Large-scale phage cultivation for commensal human gut bacteria

Phages are highly abundant in the human gut, yet most of them remain uncultured. Here, we present a gut phage isolate collection (GPIC) containing 209 phages for 42 commensal human gut bacterial species. Genome analysis of the phages identified 34 undescribed genera. We discovered 22 phages from the...

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Veröffentlicht in:	Cell host & microbe 2023-04, Vol.31 (4), p.665-677.e7
Hauptverfasser:	Shen, Juntao, Zhang, Jieqiong, Mo, Luofei, Li, Yanchen, Li, Yake, Li, Cun, Kuang, Xiaoxian, Tao, Zining, Qu, Zepeng, Wu, Lu, Chen, Junyu, Liu, Shiying, Zeng, Linfang, He, Zexi, Chen, Zuohong, Deng, Yu, Zhang, Tong, Li, Bing, Dai, Lei, Ma, Yingfei
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria - genetics Bacteriophages Gastrointestinal Microbiome - genetics host specificity human gut bacteria Humans Microbiota microbiota modulation phage cultivation phage susceptibility Symbiosis
Online-Zugang:	Volltext
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