The genetic overlap between Alzheimer’s disease, amyotrophic lateral sclerosis, Lewy body dementia, and Parkinson’s disease

Neurodegenerative diseases are a group of disorders characterized by neuronal cell death causing a variety of physical and mental problems. While these disorders can be characterized by their phenotypic presentation within the nervous system, their aetiologies differ to varying degrees. The majority...

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Veröffentlicht in:	Neurobiology of aging 2023-07, Vol.127, p.99-112
Hauptverfasser:	Wightman, Douglas P., Savage, Jeanne E., Tissink, Elleke, Romero, Cato, Jansen, Iris E., Posthuma, Danielle
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - genetics Alzheimer Disease - metabolism Alzheimer's disease Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - genetics Genetic overlap Global genetic correlation Humans Lewy body dementia Lewy Body Disease - genetics Lewy Body Disease - metabolism Local genetic correlation Neurodegenerative Diseases Parkinson Disease - genetics Parkinson Disease - metabolism Parkinson's disease
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