Successful liver transduction by re‐administration of different adeno‐associated virus vector serotypes in mice

Background Intravenous administration of adeno‐associated virus (AAV) vectors is a promising gene therapy approach for monogenic diseases. However, re‐administration of the same AAV serotype is impossible because of the induction of anti‐AAV neutralizing antibodies (NAbs). Here, we examined the feas...

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Veröffentlicht in:The journal of gene medicine 2023-08, Vol.25 (8), p.e3505-n/a
Hauptverfasser: Baatartsogt, Nemekhbayar, Kashiwakura, Yuji, Hiramoto, Takafumi, Hayakawa, Morisada, Kamoshita, Nobuhiko, Ohmori, Tsukasa
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Sprache:eng
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