Quality improvement project in a neonatal intensive care unit reduced the prevalence and duration of hypophosphatemia with significant and sustainable results

Quality improvement project in a neonatal intensive care unit reduced the prevalence and duration of hypophosphatemia with significant and sustainable results

Hypophosphatemia is associated with prolonged mechanical ventilation and may affect growth, bone mineralization, nephrocalcinosis, and mortality in preterm infants. Optimal nutrition practices may decrease risk for hypophosphatemia and improve outcome. A quality improvement project was established t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nutrition in clinical practice 2023-12, Vol.38 (6), p.1379-1391
Hauptverfasser: Lair, Cheryl S, Brown, L Steven, Edwards, Audrey, Jacob, Theresa, Brion, Luc P, Jaleel, Mambarambath
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1391
container_issue 6
container_start_page 1379
container_title Nutrition in clinical practice
container_volume 38
creator Lair, Cheryl S
Brown, L Steven
Edwards, Audrey
Jacob, Theresa
Brion, Luc P
Jaleel, Mambarambath
description Hypophosphatemia is associated with prolonged mechanical ventilation and may affect growth, bone mineralization, nephrocalcinosis, and mortality in preterm infants. Optimal nutrition practices may decrease risk for hypophosphatemia and improve outcome. A quality improvement project was established to improve parenteral and enteral phosphorus intake with the goal to decrease prevalence and duration of hypophosphatemia in the first 14 days in infants
doi_str_mv 10.1002/ncp.10986
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2800147630</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2800147630</sourcerecordid><originalsourceid>FETCH-LOGICAL-c245t-596722b387622c6ea15ac8070c61ddb690e7c822f38a8b71aff650612d3130e03</originalsourceid><addsrcrecordid>eNo9UctKxTAUDKLo9bHwByRLXVTzaNPcpYgvEETQdTlNT22kTWuTXLk_47ea62t1zoGZOcwMIcecnXPGxIUzU1qWWm2RBV_mPBN5IbbJgmmdZ4WUao_se__GGNey1LtkT5YsF0oXC_L5FKG3YU3tMM3jCgd0gabtDU2g1lGgDkcHAfp0BXTerpAamJFGZwOdsYkGGxo6TCxcQY_OIAXX0CbOEOzo6NjSbj2NUzf6qYOAgwX6YUNHvX11trUG0ssNw0cfwDqoe0zCPvbBH5KdFnqPR7_zgLzcXD9f3WUPj7f3V5cPmUlWQ1YsVSlELXWphDAKgRdgNCuZUbxparVkWBotRCs16Lrk0LaqYIqLRnLJkMkDcvqjm6y_R_ShGqw32PeQ7EdfCZ3Cy0slN9CzH6iZR-9nbKtptgPM64qzalNHleqovutI2JNf2VgP2Pwj__KXX44oiWo</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2800147630</pqid></control><display><type>article</type><title>Quality improvement project in a neonatal intensive care unit reduced the prevalence and duration of hypophosphatemia with significant and sustainable results</title><source>Wiley Online Library All Journals</source><creator>Lair, Cheryl S ; Brown, L Steven ; Edwards, Audrey ; Jacob, Theresa ; Brion, Luc P ; Jaleel, Mambarambath</creator><creatorcontrib>Lair, Cheryl S ; Brown, L Steven ; Edwards, Audrey ; Jacob, Theresa ; Brion, Luc P ; Jaleel, Mambarambath</creatorcontrib><description><![CDATA[Hypophosphatemia is associated with prolonged mechanical ventilation and may affect growth, bone mineralization, nephrocalcinosis, and mortality in preterm infants. Optimal nutrition practices may decrease risk for hypophosphatemia and improve outcome. A quality improvement project was established to improve parenteral and enteral phosphorus intake with the goal to decrease prevalence and duration of hypophosphatemia in the first 14 days in infants <32 weeks' gestation. Among 406 preterm infants, the prevalence of moderate hypophosphatemia decreased from 44% to 19% (P < 0.01) over 4 years. The median duration of moderate hypophosphatemia decreased from 72 h (48-128) to 24 (24-53) (P < 0.01). Daily intakes of parenteral calcium and phosphorus on the fourth day of life increased from 1.5 to 2.5 mEq/kg/day (P < 0.01) and 0.6 to 1.3 mmol/kg/day (P < 0.01), respectively. The median postnatal age of first serum phosphorus concentration assessment decreased from 53 h (41-64) to 32 (24-40) (P < 0.01). During this quality improvement project, reduced prevalence and duration of hypophosphatemia in infants <32 weeks' gestation in the first 14 days of life was achieved through the optimization of parenteral and enteral phosphorus intake and improved response to acute hypophosphatemia.]]></description><identifier>ISSN: 0884-5336</identifier><identifier>EISSN: 1941-2452</identifier><identifier>DOI: 10.1002/ncp.10986</identifier><identifier>PMID: 37042685</identifier><language>eng</language><publisher>United States</publisher><ispartof>Nutrition in clinical practice, 2023-12, Vol.38 (6), p.1379-1391</ispartof><rights>2023 American Society for Parenteral and Enteral Nutrition.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c245t-596722b387622c6ea15ac8070c61ddb690e7c822f38a8b71aff650612d3130e03</cites><orcidid>0000-0003-4546-7301</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37042685$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Lair, Cheryl S</creatorcontrib><creatorcontrib>Brown, L Steven</creatorcontrib><creatorcontrib>Edwards, Audrey</creatorcontrib><creatorcontrib>Jacob, Theresa</creatorcontrib><creatorcontrib>Brion, Luc P</creatorcontrib><creatorcontrib>Jaleel, Mambarambath</creatorcontrib><title>Quality improvement project in a neonatal intensive care unit reduced the prevalence and duration of hypophosphatemia with significant and sustainable results</title><title>Nutrition in clinical practice</title><addtitle>Nutr Clin Pract</addtitle><description><![CDATA[Hypophosphatemia is associated with prolonged mechanical ventilation and may affect growth, bone mineralization, nephrocalcinosis, and mortality in preterm infants. Optimal nutrition practices may decrease risk for hypophosphatemia and improve outcome. A quality improvement project was established to improve parenteral and enteral phosphorus intake with the goal to decrease prevalence and duration of hypophosphatemia in the first 14 days in infants <32 weeks' gestation. Among 406 preterm infants, the prevalence of moderate hypophosphatemia decreased from 44% to 19% (P < 0.01) over 4 years. The median duration of moderate hypophosphatemia decreased from 72 h (48-128) to 24 (24-53) (P < 0.01). Daily intakes of parenteral calcium and phosphorus on the fourth day of life increased from 1.5 to 2.5 mEq/kg/day (P < 0.01) and 0.6 to 1.3 mmol/kg/day (P < 0.01), respectively. The median postnatal age of first serum phosphorus concentration assessment decreased from 53 h (41-64) to 32 (24-40) (P < 0.01). During this quality improvement project, reduced prevalence and duration of hypophosphatemia in infants <32 weeks' gestation in the first 14 days of life was achieved through the optimization of parenteral and enteral phosphorus intake and improved response to acute hypophosphatemia.]]></description><issn>0884-5336</issn><issn>1941-2452</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNo9UctKxTAUDKLo9bHwByRLXVTzaNPcpYgvEETQdTlNT22kTWuTXLk_47ea62t1zoGZOcwMIcecnXPGxIUzU1qWWm2RBV_mPBN5IbbJgmmdZ4WUao_se__GGNey1LtkT5YsF0oXC_L5FKG3YU3tMM3jCgd0gabtDU2g1lGgDkcHAfp0BXTerpAamJFGZwOdsYkGGxo6TCxcQY_OIAXX0CbOEOzo6NjSbj2NUzf6qYOAgwX6YUNHvX11trUG0ssNw0cfwDqoe0zCPvbBH5KdFnqPR7_zgLzcXD9f3WUPj7f3V5cPmUlWQ1YsVSlELXWphDAKgRdgNCuZUbxparVkWBotRCs16Lrk0LaqYIqLRnLJkMkDcvqjm6y_R_ShGqw32PeQ7EdfCZ3Cy0slN9CzH6iZR-9nbKtptgPM64qzalNHleqovutI2JNf2VgP2Pwj__KXX44oiWo</recordid><startdate>20231201</startdate><enddate>20231201</enddate><creator>Lair, Cheryl S</creator><creator>Brown, L Steven</creator><creator>Edwards, Audrey</creator><creator>Jacob, Theresa</creator><creator>Brion, Luc P</creator><creator>Jaleel, Mambarambath</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4546-7301</orcidid></search><sort><creationdate>20231201</creationdate><title>Quality improvement project in a neonatal intensive care unit reduced the prevalence and duration of hypophosphatemia with significant and sustainable results</title><author>Lair, Cheryl S ; Brown, L Steven ; Edwards, Audrey ; Jacob, Theresa ; Brion, Luc P ; Jaleel, Mambarambath</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c245t-596722b387622c6ea15ac8070c61ddb690e7c822f38a8b71aff650612d3130e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Lair, Cheryl S</creatorcontrib><creatorcontrib>Brown, L Steven</creatorcontrib><creatorcontrib>Edwards, Audrey</creatorcontrib><creatorcontrib>Jacob, Theresa</creatorcontrib><creatorcontrib>Brion, Luc P</creatorcontrib><creatorcontrib>Jaleel, Mambarambath</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Nutrition in clinical practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Lair, Cheryl S</au><au>Brown, L Steven</au><au>Edwards, Audrey</au><au>Jacob, Theresa</au><au>Brion, Luc P</au><au>Jaleel, Mambarambath</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Quality improvement project in a neonatal intensive care unit reduced the prevalence and duration of hypophosphatemia with significant and sustainable results</atitle><jtitle>Nutrition in clinical practice</jtitle><addtitle>Nutr Clin Pract</addtitle><date>2023-12-01</date><risdate>2023</risdate><volume>38</volume><issue>6</issue><spage>1379</spage><epage>1391</epage><pages>1379-1391</pages><issn>0884-5336</issn><eissn>1941-2452</eissn><abstract><![CDATA[Hypophosphatemia is associated with prolonged mechanical ventilation and may affect growth, bone mineralization, nephrocalcinosis, and mortality in preterm infants. Optimal nutrition practices may decrease risk for hypophosphatemia and improve outcome. A quality improvement project was established to improve parenteral and enteral phosphorus intake with the goal to decrease prevalence and duration of hypophosphatemia in the first 14 days in infants <32 weeks' gestation. Among 406 preterm infants, the prevalence of moderate hypophosphatemia decreased from 44% to 19% (P < 0.01) over 4 years. The median duration of moderate hypophosphatemia decreased from 72 h (48-128) to 24 (24-53) (P < 0.01). Daily intakes of parenteral calcium and phosphorus on the fourth day of life increased from 1.5 to 2.5 mEq/kg/day (P < 0.01) and 0.6 to 1.3 mmol/kg/day (P < 0.01), respectively. The median postnatal age of first serum phosphorus concentration assessment decreased from 53 h (41-64) to 32 (24-40) (P < 0.01). During this quality improvement project, reduced prevalence and duration of hypophosphatemia in infants <32 weeks' gestation in the first 14 days of life was achieved through the optimization of parenteral and enteral phosphorus intake and improved response to acute hypophosphatemia.]]></abstract><cop>United States</cop><pmid>37042685</pmid><doi>10.1002/ncp.10986</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0003-4546-7301</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 0884-5336
ispartof Nutrition in clinical practice, 2023-12, Vol.38 (6), p.1379-1391
issn 0884-5336
1941-2452
language eng
recordid cdi_proquest_miscellaneous_2800147630
source Wiley Online Library All Journals
title Quality improvement project in a neonatal intensive care unit reduced the prevalence and duration of hypophosphatemia with significant and sustainable results
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T16%3A57%3A27IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Quality%20improvement%20project%20in%20a%20neonatal%20intensive%20care%20unit%20reduced%20the%20prevalence%20and%20duration%20of%20hypophosphatemia%20with%20significant%20and%20sustainable%20results&rft.jtitle=Nutrition%20in%20clinical%20practice&rft.au=Lair,%20Cheryl%20S&rft.date=2023-12-01&rft.volume=38&rft.issue=6&rft.spage=1379&rft.epage=1391&rft.pages=1379-1391&rft.issn=0884-5336&rft.eissn=1941-2452&rft_id=info:doi/10.1002/ncp.10986&rft_dat=%3Cproquest_cross%3E2800147630%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2800147630&rft_id=info:pmid/37042685&rfr_iscdi=true