Oxidative Stress Reactions in Women of Reproductive Age with Metabolic Syndrome
We analyzed the levels of LPO products and antioxidant defense components in women with the metabolic syndrome. Women with the metabolic syndrome had higher values of substrates with unsaturated double bonds and final TBA-reactive substances in comparison with the control group and higher levels of...
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Veröffentlicht in: | Bulletin of experimental biology and medicine 2023-03, Vol.174 (5), p.601-604 |
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creator | Darenskaya, M. A. Belenkaya, L. V. Atalyan, A. V. Danusevich, I. N. Lazareva, L. M. Nadelyaeva, Ya. G. Kolesnikova, L. I. |
description | We analyzed the levels of LPO products and antioxidant defense components in women with the metabolic syndrome. Women with the metabolic syndrome had higher values of substrates with unsaturated double bonds and final TBA-reactive substances in comparison with the control group and higher levels of unsaturated double bonds, primary and end products of LPO, and retinol in comparison with the reference group (women with less than 3 signs of metabolic syndrome). No statistically significant differences between the groups were revealed while estimating the coefficient of oxidative stress; however, there was a tendency to an increase in the median value of this parameter in the group with metabolic syndrome. Thus, the results of the study indicate the activity of LPO reactions at different stages in women of reproductive age with the metabolic syndrome, which points to the necessity to evaluate and monitor the content of these metabolites in the patients of this cohort for the purpose of prevention and treatment. |
doi_str_mv | 10.1007/s10517-023-05754-w |
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A. ; Belenkaya, L. V. ; Atalyan, A. V. ; Danusevich, I. N. ; Lazareva, L. M. ; Nadelyaeva, Ya. G. ; Kolesnikova, L. I.</creator><creatorcontrib>Darenskaya, M. A. ; Belenkaya, L. V. ; Atalyan, A. V. ; Danusevich, I. N. ; Lazareva, L. M. ; Nadelyaeva, Ya. G. ; Kolesnikova, L. I.</creatorcontrib><description>We analyzed the levels of LPO products and antioxidant defense components in women with the metabolic syndrome. Women with the metabolic syndrome had higher values of substrates with unsaturated double bonds and final TBA-reactive substances in comparison with the control group and higher levels of unsaturated double bonds, primary and end products of LPO, and retinol in comparison with the reference group (women with less than 3 signs of metabolic syndrome). No statistically significant differences between the groups were revealed while estimating the coefficient of oxidative stress; however, there was a tendency to an increase in the median value of this parameter in the group with metabolic syndrome. 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A.</au><au>Belenkaya, L. V.</au><au>Atalyan, A. V.</au><au>Danusevich, I. N.</au><au>Lazareva, L. M.</au><au>Nadelyaeva, Ya. G.</au><au>Kolesnikova, L. I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Oxidative Stress Reactions in Women of Reproductive Age with Metabolic Syndrome</atitle><jtitle>Bulletin of experimental biology and medicine</jtitle><stitle>Bull Exp Biol Med</stitle><addtitle>Bull Exp Biol Med</addtitle><date>2023-03-01</date><risdate>2023</risdate><volume>174</volume><issue>5</issue><spage>601</spage><epage>604</epage><pages>601-604</pages><issn>0007-4888</issn><eissn>1573-8221</eissn><abstract>We analyzed the levels of LPO products and antioxidant defense components in women with the metabolic syndrome. Women with the metabolic syndrome had higher values of substrates with unsaturated double bonds and final TBA-reactive substances in comparison with the control group and higher levels of unsaturated double bonds, primary and end products of LPO, and retinol in comparison with the reference group (women with less than 3 signs of metabolic syndrome). No statistically significant differences between the groups were revealed while estimating the coefficient of oxidative stress; however, there was a tendency to an increase in the median value of this parameter in the group with metabolic syndrome. 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subjects | Antioxidants Antioxidants - metabolism Biomedical and Life Sciences Biomedicine Cell Biology Dietary fiber Female Humans Internal Medicine Laboratory Medicine Lipid Peroxidation Metabolic Syndrome Metabolites Oxidative Stress Pathology Retinoids Statistical analysis Vitamin A |
title | Oxidative Stress Reactions in Women of Reproductive Age with Metabolic Syndrome |
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