Oxidative Stress Reactions in Women of Reproductive Age with Metabolic Syndrome

We analyzed the levels of LPO products and antioxidant defense components in women with the metabolic syndrome. Women with the metabolic syndrome had higher values of substrates with unsaturated double bonds and final TBA-reactive substances in comparison with the control group and higher levels of...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bulletin of experimental biology and medicine 2023-03, Vol.174 (5), p.601-604
Hauptverfasser: Darenskaya, M. A., Belenkaya, L. V., Atalyan, A. V., Danusevich, I. N., Lazareva, L. M., Nadelyaeva, Ya. G., Kolesnikova, L. I.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 604
container_issue 5
container_start_page 601
container_title Bulletin of experimental biology and medicine
container_volume 174
creator Darenskaya, M. A.
Belenkaya, L. V.
Atalyan, A. V.
Danusevich, I. N.
Lazareva, L. M.
Nadelyaeva, Ya. G.
Kolesnikova, L. I.
description We analyzed the levels of LPO products and antioxidant defense components in women with the metabolic syndrome. Women with the metabolic syndrome had higher values of substrates with unsaturated double bonds and final TBA-reactive substances in comparison with the control group and higher levels of unsaturated double bonds, primary and end products of LPO, and retinol in comparison with the reference group (women with less than 3 signs of metabolic syndrome). No statistically significant differences between the groups were revealed while estimating the coefficient of oxidative stress; however, there was a tendency to an increase in the median value of this parameter in the group with metabolic syndrome. Thus, the results of the study indicate the activity of LPO reactions at different stages in women of reproductive age with the metabolic syndrome, which points to the necessity to evaluate and monitor the content of these metabolites in the patients of this cohort for the purpose of prevention and treatment.
doi_str_mv 10.1007/s10517-023-05754-w
format Article
fullrecord <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_2799827793</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A757804630</galeid><sourcerecordid>A757804630</sourcerecordid><originalsourceid>FETCH-LOGICAL-c473t-64f85a9e877db42ab16a91119b647643ada741f5a2f30840a163ff00b44578a73</originalsourceid><addsrcrecordid>eNp9kW9rFDEQxoMo9qx-AV_IgiC-2Tr5szvZl0fRKlQOrOLLkN1N7lJ2k5rs9uy3b-6uWisiCYSZ_J7JTB5CXlI4oQD4LlGoKJbAeAkVVqLcPiILWiEvJWP0MVlApkohpTwiz1K63IVQ06fkiCMIyHtBVqufrteTuzbFxRRNSsUXo7vJBZ8K54vvYTS-CDZnr2Lo525PLtem2LppU3w2k27D4Lri4sb3McPPyROrh2Re3J3H5NuH919PP5bnq7NPp8vzshPIp7IWVla6MRKxbwXTLa11Qylt2lpgLbjuNQpqK80sBylA05pbC9AKUaHUyI_J20Pd3NaP2aRJjS51Zhi0N2FOimHTSIbY8Iy-_gu9DHP0uTvFJFRMIgW8p9Z6MMp5G6aou11RtcT8JoiaQ6ZO_kHl1ZvRdcEb63L-geDNH4KN0cO0SWGY9z_8EGQHsIshpWisuopu1PFGUVA7u9XBbpXtVnu71TaLXt2NNrej6X9LfvmbAX4AUr7yaxPvZ_9P2VvHe7Ge</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2805287107</pqid></control><display><type>article</type><title>Oxidative Stress Reactions in Women of Reproductive Age with Metabolic Syndrome</title><source>MEDLINE</source><source>SpringerLink Journals - AutoHoldings</source><creator>Darenskaya, M. A. ; Belenkaya, L. V. ; Atalyan, A. V. ; Danusevich, I. N. ; Lazareva, L. M. ; Nadelyaeva, Ya. G. ; Kolesnikova, L. I.</creator><creatorcontrib>Darenskaya, M. A. ; Belenkaya, L. V. ; Atalyan, A. V. ; Danusevich, I. N. ; Lazareva, L. M. ; Nadelyaeva, Ya. G. ; Kolesnikova, L. I.</creatorcontrib><description>We analyzed the levels of LPO products and antioxidant defense components in women with the metabolic syndrome. Women with the metabolic syndrome had higher values of substrates with unsaturated double bonds and final TBA-reactive substances in comparison with the control group and higher levels of unsaturated double bonds, primary and end products of LPO, and retinol in comparison with the reference group (women with less than 3 signs of metabolic syndrome). No statistically significant differences between the groups were revealed while estimating the coefficient of oxidative stress; however, there was a tendency to an increase in the median value of this parameter in the group with metabolic syndrome. Thus, the results of the study indicate the activity of LPO reactions at different stages in women of reproductive age with the metabolic syndrome, which points to the necessity to evaluate and monitor the content of these metabolites in the patients of this cohort for the purpose of prevention and treatment.</description><identifier>ISSN: 0007-4888</identifier><identifier>EISSN: 1573-8221</identifier><identifier>DOI: 10.1007/s10517-023-05754-w</identifier><identifier>PMID: 37040040</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Antioxidants ; Antioxidants - metabolism ; Biomedical and Life Sciences ; Biomedicine ; Cell Biology ; Dietary fiber ; Female ; Humans ; Internal Medicine ; Laboratory Medicine ; Lipid Peroxidation ; Metabolic Syndrome ; Metabolites ; Oxidative Stress ; Pathology ; Retinoids ; Statistical analysis ; Vitamin A</subject><ispartof>Bulletin of experimental biology and medicine, 2023-03, Vol.174 (5), p.601-604</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. Springer Science+Business Media, LLC, part of Springer Nature.</rights><rights>COPYRIGHT 2023 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c473t-64f85a9e877db42ab16a91119b647643ada741f5a2f30840a163ff00b44578a73</citedby><cites>FETCH-LOGICAL-c473t-64f85a9e877db42ab16a91119b647643ada741f5a2f30840a163ff00b44578a73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10517-023-05754-w$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10517-023-05754-w$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37040040$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Darenskaya, M. A.</creatorcontrib><creatorcontrib>Belenkaya, L. V.</creatorcontrib><creatorcontrib>Atalyan, A. V.</creatorcontrib><creatorcontrib>Danusevich, I. N.</creatorcontrib><creatorcontrib>Lazareva, L. M.</creatorcontrib><creatorcontrib>Nadelyaeva, Ya. G.</creatorcontrib><creatorcontrib>Kolesnikova, L. I.</creatorcontrib><title>Oxidative Stress Reactions in Women of Reproductive Age with Metabolic Syndrome</title><title>Bulletin of experimental biology and medicine</title><addtitle>Bull Exp Biol Med</addtitle><addtitle>Bull Exp Biol Med</addtitle><description>We analyzed the levels of LPO products and antioxidant defense components in women with the metabolic syndrome. Women with the metabolic syndrome had higher values of substrates with unsaturated double bonds and final TBA-reactive substances in comparison with the control group and higher levels of unsaturated double bonds, primary and end products of LPO, and retinol in comparison with the reference group (women with less than 3 signs of metabolic syndrome). No statistically significant differences between the groups were revealed while estimating the coefficient of oxidative stress; however, there was a tendency to an increase in the median value of this parameter in the group with metabolic syndrome. Thus, the results of the study indicate the activity of LPO reactions at different stages in women of reproductive age with the metabolic syndrome, which points to the necessity to evaluate and monitor the content of these metabolites in the patients of this cohort for the purpose of prevention and treatment.</description><subject>Antioxidants</subject><subject>Antioxidants - metabolism</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cell Biology</subject><subject>Dietary fiber</subject><subject>Female</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Laboratory Medicine</subject><subject>Lipid Peroxidation</subject><subject>Metabolic Syndrome</subject><subject>Metabolites</subject><subject>Oxidative Stress</subject><subject>Pathology</subject><subject>Retinoids</subject><subject>Statistical analysis</subject><subject>Vitamin A</subject><issn>0007-4888</issn><issn>1573-8221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kW9rFDEQxoMo9qx-AV_IgiC-2Tr5szvZl0fRKlQOrOLLkN1N7lJ2k5rs9uy3b-6uWisiCYSZ_J7JTB5CXlI4oQD4LlGoKJbAeAkVVqLcPiILWiEvJWP0MVlApkohpTwiz1K63IVQ06fkiCMIyHtBVqufrteTuzbFxRRNSsUXo7vJBZ8K54vvYTS-CDZnr2Lo525PLtem2LppU3w2k27D4Lri4sb3McPPyROrh2Re3J3H5NuH919PP5bnq7NPp8vzshPIp7IWVla6MRKxbwXTLa11Qylt2lpgLbjuNQpqK80sBylA05pbC9AKUaHUyI_J20Pd3NaP2aRJjS51Zhi0N2FOimHTSIbY8Iy-_gu9DHP0uTvFJFRMIgW8p9Z6MMp5G6aou11RtcT8JoiaQ6ZO_kHl1ZvRdcEb63L-geDNH4KN0cO0SWGY9z_8EGQHsIshpWisuopu1PFGUVA7u9XBbpXtVnu71TaLXt2NNrej6X9LfvmbAX4AUr7yaxPvZ_9P2VvHe7Ge</recordid><startdate>20230301</startdate><enddate>20230301</enddate><creator>Darenskaya, M. A.</creator><creator>Belenkaya, L. V.</creator><creator>Atalyan, A. V.</creator><creator>Danusevich, I. N.</creator><creator>Lazareva, L. M.</creator><creator>Nadelyaeva, Ya. G.</creator><creator>Kolesnikova, L. I.</creator><general>Springer US</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20230301</creationdate><title>Oxidative Stress Reactions in Women of Reproductive Age with Metabolic Syndrome</title><author>Darenskaya, M. A. ; Belenkaya, L. V. ; Atalyan, A. V. ; Danusevich, I. N. ; Lazareva, L. M. ; Nadelyaeva, Ya. G. ; Kolesnikova, L. I.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c473t-64f85a9e877db42ab16a91119b647643ada741f5a2f30840a163ff00b44578a73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Antioxidants</topic><topic>Antioxidants - metabolism</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Cell Biology</topic><topic>Dietary fiber</topic><topic>Female</topic><topic>Humans</topic><topic>Internal Medicine</topic><topic>Laboratory Medicine</topic><topic>Lipid Peroxidation</topic><topic>Metabolic Syndrome</topic><topic>Metabolites</topic><topic>Oxidative Stress</topic><topic>Pathology</topic><topic>Retinoids</topic><topic>Statistical analysis</topic><topic>Vitamin A</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Darenskaya, M. A.</creatorcontrib><creatorcontrib>Belenkaya, L. V.</creatorcontrib><creatorcontrib>Atalyan, A. V.</creatorcontrib><creatorcontrib>Danusevich, I. N.</creatorcontrib><creatorcontrib>Lazareva, L. M.</creatorcontrib><creatorcontrib>Nadelyaeva, Ya. G.</creatorcontrib><creatorcontrib>Kolesnikova, L. I.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Bulletin of experimental biology and medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Darenskaya, M. A.</au><au>Belenkaya, L. V.</au><au>Atalyan, A. V.</au><au>Danusevich, I. N.</au><au>Lazareva, L. M.</au><au>Nadelyaeva, Ya. G.</au><au>Kolesnikova, L. I.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Oxidative Stress Reactions in Women of Reproductive Age with Metabolic Syndrome</atitle><jtitle>Bulletin of experimental biology and medicine</jtitle><stitle>Bull Exp Biol Med</stitle><addtitle>Bull Exp Biol Med</addtitle><date>2023-03-01</date><risdate>2023</risdate><volume>174</volume><issue>5</issue><spage>601</spage><epage>604</epage><pages>601-604</pages><issn>0007-4888</issn><eissn>1573-8221</eissn><abstract>We analyzed the levels of LPO products and antioxidant defense components in women with the metabolic syndrome. Women with the metabolic syndrome had higher values of substrates with unsaturated double bonds and final TBA-reactive substances in comparison with the control group and higher levels of unsaturated double bonds, primary and end products of LPO, and retinol in comparison with the reference group (women with less than 3 signs of metabolic syndrome). No statistically significant differences between the groups were revealed while estimating the coefficient of oxidative stress; however, there was a tendency to an increase in the median value of this parameter in the group with metabolic syndrome. Thus, the results of the study indicate the activity of LPO reactions at different stages in women of reproductive age with the metabolic syndrome, which points to the necessity to evaluate and monitor the content of these metabolites in the patients of this cohort for the purpose of prevention and treatment.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>37040040</pmid><doi>10.1007/s10517-023-05754-w</doi><tpages>4</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0007-4888
ispartof Bulletin of experimental biology and medicine, 2023-03, Vol.174 (5), p.601-604
issn 0007-4888
1573-8221
language eng
recordid cdi_proquest_miscellaneous_2799827793
source MEDLINE; SpringerLink Journals - AutoHoldings
subjects Antioxidants
Antioxidants - metabolism
Biomedical and Life Sciences
Biomedicine
Cell Biology
Dietary fiber
Female
Humans
Internal Medicine
Laboratory Medicine
Lipid Peroxidation
Metabolic Syndrome
Metabolites
Oxidative Stress
Pathology
Retinoids
Statistical analysis
Vitamin A
title Oxidative Stress Reactions in Women of Reproductive Age with Metabolic Syndrome
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-06T15%3A04%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Oxidative%20Stress%20Reactions%20in%20Women%20of%20Reproductive%20Age%20with%20Metabolic%20Syndrome&rft.jtitle=Bulletin%20of%20experimental%20biology%20and%20medicine&rft.au=Darenskaya,%20M.%20A.&rft.date=2023-03-01&rft.volume=174&rft.issue=5&rft.spage=601&rft.epage=604&rft.pages=601-604&rft.issn=0007-4888&rft.eissn=1573-8221&rft_id=info:doi/10.1007/s10517-023-05754-w&rft_dat=%3Cgale_proqu%3EA757804630%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2805287107&rft_id=info:pmid/37040040&rft_galeid=A757804630&rfr_iscdi=true