Identification of MYB gene family and functional analysis of GhMYB4 in cotton (Gossypium spp.)
Myeloblastosis ( MYB ) transcription factors (TFs) form a large gene family involved in a variety of biological processes in plants. Little is known about their roles in the development of cotton pigment glands. In this study, 646 MYB members were identified in Gossypium hirsutum genome and phylogen...
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| creator | Dai, Yuanli Liu, Shang Zuo, Dongyun Wang, Qiaolian Lv, Limin Zhang, Youping Cheng, Hailiang Yu, John Z. Song, Guoli |
| description | Myeloblastosis (
MYB
) transcription factors (TFs) form a large gene family involved in a variety of biological processes in plants. Little is known about their roles in the development of cotton pigment glands. In this study, 646
MYB
members were identified in
Gossypium hirsutum
genome and phylogenetic classification was analyzed. Evolution analysis revealed assymetric evolution of
GhMYBs
during polyploidization and sequence divergence of MYBs in
G. hirustum
was preferentially happend in D sub-genome. WGCNA (weighted gene co-expression network analysis) showed that four modules had potential relationship with gland development or gossypol biosynthesis in cotton. Eight differentially expressed
GhMYB
genes were identified by screening transcriptome data of three pairs of glanded and glandless cotton lines. Of these, four were selected as candidate genes for cotton pigment gland formation or gossypol biosynthesis by qRT-PCR assay. Silencing of
GH_A11G1361
(
GhMYB4
) downregulated expression of multiple genes in gossypol biosynthesis pathway, indicating it could be involved in gossypol biosynthesis. The potential protein interaction network suggests that several MYBs may have indirect interaction with
GhMYC2
-like, a key regulator of pigment gland formation. Our study was the systematic analysis of
MYB
genes in cotton pigment gland development, providing candidate genes for further study on the roles of cotton
MYB
genes in pigment gland formation, gossypol biosynthesis and future crop plant improvement. |
| doi_str_mv | 10.1007/s00438-023-02005-5 |
| format | Article |
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MYB
) transcription factors (TFs) form a large gene family involved in a variety of biological processes in plants. Little is known about their roles in the development of cotton pigment glands. In this study, 646
MYB
members were identified in
Gossypium hirsutum
genome and phylogenetic classification was analyzed. Evolution analysis revealed assymetric evolution of
GhMYBs
during polyploidization and sequence divergence of MYBs in
G. hirustum
was preferentially happend in D sub-genome. WGCNA (weighted gene co-expression network analysis) showed that four modules had potential relationship with gland development or gossypol biosynthesis in cotton. Eight differentially expressed
GhMYB
genes were identified by screening transcriptome data of three pairs of glanded and glandless cotton lines. Of these, four were selected as candidate genes for cotton pigment gland formation or gossypol biosynthesis by qRT-PCR assay. Silencing of
GH_A11G1361
(
GhMYB4
) downregulated expression of multiple genes in gossypol biosynthesis pathway, indicating it could be involved in gossypol biosynthesis. The potential protein interaction network suggests that several MYBs may have indirect interaction with
GhMYC2
-like, a key regulator of pigment gland formation. Our study was the systematic analysis of
MYB
genes in cotton pigment gland development, providing candidate genes for further study on the roles of cotton
MYB
genes in pigment gland formation, gossypol biosynthesis and future crop plant improvement.</description><identifier>ISSN: 1617-4615</identifier><identifier>EISSN: 1617-4623</identifier><identifier>DOI: 10.1007/s00438-023-02005-5</identifier><identifier>PMID: 37027022</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Animal Genetics and Genomics ; Biochemistry ; Biomedical and Life Sciences ; Biosynthesis ; Cotton ; crops ; Divergence ; Gene Expression Regulation, Plant ; Genes ; Genes, myb - genetics ; Genomes ; genomics ; Glands ; Gossypium - metabolism ; Gossypium hirsutum ; Gossypol ; Gossypol - metabolism ; Human Genetics ; Life Sciences ; Microbial Genetics and Genomics ; MYB gene ; Original Article ; Phylogeny ; Plant Genetics and Genomics ; plant improvement ; Polyploidy ; Protein biosynthesis ; Transcription factors ; Transcription Factors - genetics ; Transcription Factors - metabolism ; transcriptome ; Transcriptomes</subject><ispartof>Molecular genetics and genomics : MGG, 2023-05, Vol.298 (3), p.755-766</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c408t-2f0966759c770d4add764c365c97ae04230fce65cb1207141702b3758aa272e83</citedby><cites>FETCH-LOGICAL-c408t-2f0966759c770d4add764c365c97ae04230fce65cb1207141702b3758aa272e83</cites><orcidid>0000-0003-3236-9286</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00438-023-02005-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00438-023-02005-5$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37027022$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dai, Yuanli</creatorcontrib><creatorcontrib>Liu, Shang</creatorcontrib><creatorcontrib>Zuo, Dongyun</creatorcontrib><creatorcontrib>Wang, Qiaolian</creatorcontrib><creatorcontrib>Lv, Limin</creatorcontrib><creatorcontrib>Zhang, Youping</creatorcontrib><creatorcontrib>Cheng, Hailiang</creatorcontrib><creatorcontrib>Yu, John Z.</creatorcontrib><creatorcontrib>Song, Guoli</creatorcontrib><title>Identification of MYB gene family and functional analysis of GhMYB4 in cotton (Gossypium spp.)</title><title>Molecular genetics and genomics : MGG</title><addtitle>Mol Genet Genomics</addtitle><addtitle>Mol Genet Genomics</addtitle><description>Myeloblastosis (
MYB
) transcription factors (TFs) form a large gene family involved in a variety of biological processes in plants. Little is known about their roles in the development of cotton pigment glands. In this study, 646
MYB
members were identified in
Gossypium hirsutum
genome and phylogenetic classification was analyzed. Evolution analysis revealed assymetric evolution of
GhMYBs
during polyploidization and sequence divergence of MYBs in
G. hirustum
was preferentially happend in D sub-genome. WGCNA (weighted gene co-expression network analysis) showed that four modules had potential relationship with gland development or gossypol biosynthesis in cotton. Eight differentially expressed
GhMYB
genes were identified by screening transcriptome data of three pairs of glanded and glandless cotton lines. Of these, four were selected as candidate genes for cotton pigment gland formation or gossypol biosynthesis by qRT-PCR assay. Silencing of
GH_A11G1361
(
GhMYB4
) downregulated expression of multiple genes in gossypol biosynthesis pathway, indicating it could be involved in gossypol biosynthesis. The potential protein interaction network suggests that several MYBs may have indirect interaction with
GhMYC2
-like, a key regulator of pigment gland formation. Our study was the systematic analysis of
MYB
genes in cotton pigment gland development, providing candidate genes for further study on the roles of cotton
MYB
genes in pigment gland formation, gossypol biosynthesis and future crop plant improvement.</description><subject>Animal Genetics and Genomics</subject><subject>Biochemistry</subject><subject>Biomedical and Life Sciences</subject><subject>Biosynthesis</subject><subject>Cotton</subject><subject>crops</subject><subject>Divergence</subject><subject>Gene Expression Regulation, Plant</subject><subject>Genes</subject><subject>Genes, myb - genetics</subject><subject>Genomes</subject><subject>genomics</subject><subject>Glands</subject><subject>Gossypium - metabolism</subject><subject>Gossypium hirsutum</subject><subject>Gossypol</subject><subject>Gossypol - metabolism</subject><subject>Human Genetics</subject><subject>Life Sciences</subject><subject>Microbial Genetics and Genomics</subject><subject>MYB gene</subject><subject>Original Article</subject><subject>Phylogeny</subject><subject>Plant Genetics and Genomics</subject><subject>plant improvement</subject><subject>Polyploidy</subject><subject>Protein biosynthesis</subject><subject>Transcription factors</subject><subject>Transcription Factors - 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genetics</topic><topic>Genomes</topic><topic>genomics</topic><topic>Glands</topic><topic>Gossypium - metabolism</topic><topic>Gossypium hirsutum</topic><topic>Gossypol</topic><topic>Gossypol - metabolism</topic><topic>Human Genetics</topic><topic>Life Sciences</topic><topic>Microbial Genetics and Genomics</topic><topic>MYB gene</topic><topic>Original Article</topic><topic>Phylogeny</topic><topic>Plant Genetics and Genomics</topic><topic>plant improvement</topic><topic>Polyploidy</topic><topic>Protein biosynthesis</topic><topic>Transcription factors</topic><topic>Transcription Factors - genetics</topic><topic>Transcription Factors - metabolism</topic><topic>transcriptome</topic><topic>Transcriptomes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dai, Yuanli</creatorcontrib><creatorcontrib>Liu, Shang</creatorcontrib><creatorcontrib>Zuo, Dongyun</creatorcontrib><creatorcontrib>Wang, Qiaolian</creatorcontrib><creatorcontrib>Lv, Limin</creatorcontrib><creatorcontrib>Zhang, Youping</creatorcontrib><creatorcontrib>Cheng, Hailiang</creatorcontrib><creatorcontrib>Yu, John Z.</creatorcontrib><creatorcontrib>Song, Guoli</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>AGRICOLA</collection><collection>AGRICOLA - Academic</collection><jtitle>Molecular genetics and genomics : MGG</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dai, Yuanli</au><au>Liu, Shang</au><au>Zuo, Dongyun</au><au>Wang, Qiaolian</au><au>Lv, Limin</au><au>Zhang, Youping</au><au>Cheng, Hailiang</au><au>Yu, John Z.</au><au>Song, Guoli</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Identification of MYB gene family and functional analysis of GhMYB4 in cotton (Gossypium spp.)</atitle><jtitle>Molecular genetics and genomics : MGG</jtitle><stitle>Mol Genet Genomics</stitle><addtitle>Mol Genet Genomics</addtitle><date>2023-05-01</date><risdate>2023</risdate><volume>298</volume><issue>3</issue><spage>755</spage><epage>766</epage><pages>755-766</pages><issn>1617-4615</issn><eissn>1617-4623</eissn><abstract>Myeloblastosis (
MYB
) transcription factors (TFs) form a large gene family involved in a variety of biological processes in plants. Little is known about their roles in the development of cotton pigment glands. In this study, 646
MYB
members were identified in
Gossypium hirsutum
genome and phylogenetic classification was analyzed. Evolution analysis revealed assymetric evolution of
GhMYBs
during polyploidization and sequence divergence of MYBs in
G. hirustum
was preferentially happend in D sub-genome. WGCNA (weighted gene co-expression network analysis) showed that four modules had potential relationship with gland development or gossypol biosynthesis in cotton. Eight differentially expressed
GhMYB
genes were identified by screening transcriptome data of three pairs of glanded and glandless cotton lines. Of these, four were selected as candidate genes for cotton pigment gland formation or gossypol biosynthesis by qRT-PCR assay. Silencing of
GH_A11G1361
(
GhMYB4
) downregulated expression of multiple genes in gossypol biosynthesis pathway, indicating it could be involved in gossypol biosynthesis. The potential protein interaction network suggests that several MYBs may have indirect interaction with
GhMYC2
-like, a key regulator of pigment gland formation. Our study was the systematic analysis of
MYB
genes in cotton pigment gland development, providing candidate genes for further study on the roles of cotton
MYB
genes in pigment gland formation, gossypol biosynthesis and future crop plant improvement.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>37027022</pmid><doi>10.1007/s00438-023-02005-5</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0003-3236-9286</orcidid></addata></record> |
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| ispartof | Molecular genetics and genomics : MGG, 2023-05, Vol.298 (3), p.755-766 |
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| language | eng |
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| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Animal Genetics and Genomics Biochemistry Biomedical and Life Sciences Biosynthesis Cotton crops Divergence Gene Expression Regulation, Plant Genes Genes, myb - genetics Genomes genomics Glands Gossypium - metabolism Gossypium hirsutum Gossypol Gossypol - metabolism Human Genetics Life Sciences Microbial Genetics and Genomics MYB gene Original Article Phylogeny Plant Genetics and Genomics plant improvement Polyploidy Protein biosynthesis Transcription factors Transcription Factors - genetics Transcription Factors - metabolism transcriptome Transcriptomes |
| title | Identification of MYB gene family and functional analysis of GhMYB4 in cotton (Gossypium spp.) |
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