Oligodendrocyte-derived transcellular signaling regulates axonal energy metabolism

The unique morphology and functionality of central nervous system (CNS) neurons necessitate specialized mechanisms to maintain energy metabolism throughout long axons and extensive terminals. Oligodendrocytes (OLs) enwrap CNS axons with myelin sheaths in a multilamellar fashion. Apart from their wel...

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Veröffentlicht in:	Current opinion in neurobiology 2023-06, Vol.80, p.102722-102722, Article 102722
Hauptverfasser:	Li, Sunan, Sheng, Zu-Hang
Format:	Artikel
Sprache:	eng
Schlagworte:	ATP supply Axonal bioenergetics Axons - physiology Central Nervous System - physiology Energy metabolism Energy Metabolism - physiology Exosome Glycolysis Metabolite shuttling Mitochondria Myelin Myelin Sheath - metabolism Neurodegeneration Oligodendrocyte Oligodendroglia
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