Thyrotropin Receptor Antagonism by a Novel Small Molecule: Preclinical In Vitro Observations

Treatment of Graves' hyperthyroidism (GH) and Graves' orbitopathy (GO) is far from adequate, and hence, new substances that specifically target the autoantigens in GH/GO are warranted. This study determined the preclinical efficacy of SYD5115, a novel low-molecular-weight compound that inh...

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Veröffentlicht in:	Thyroid (New York, N.Y.) N.Y.), 2023-06, Vol.33 (6), p.732-742
Hauptverfasser:	Kahaly, George J, Steiner, Lisa, van der Lee, Miranda M C, van Achterberg, Tanja A E, Arends, Roel J, Karstens, Willem F J, Weirauch, Tobias, Henseling, Jil, Frommer, Lara, Wolf, Jan, George, Augustine
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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